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|本期目录/Table of Contents|

吸烟、内皮细胞功能紊乱和动脉粥样硬化

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2015年第4期
页码:
483-485
栏目:
综述
出版日期:
2015-04-20

文章信息/Info

Title:
Cigarette smoking, endothelial dysfunction and atherosclerosis
作者:
赖 斌; 魏玉杰; 刘惠亮
(武警总医院心内科，北京 100039)
Author(s):
LAI Bin;  WEI Yu-jie;  LIU Hui-liang
(Department of Cardiology, General Hospital, Armed Police Forces, Beijing 100039, China)
关键词:
吸烟; 内皮细胞功能紊乱; 动脉粥样硬化
Keywords:
cigarette smoking;  endothelial dysfunction;  atherosclerosis
分类号:
R163
DOI:
-
文献标识码:
A
摘要:
吸烟是动脉粥样硬化(AS)的主要危险因素，而内皮细胞功能紊乱被认为是AS形成的关键起始因素。吸烟可通过导致内皮细胞功能紊乱，破坏内皮细胞的舒张、抗凝、抗炎等功能，增加氧化应激从而促使AS的形成。
Abstract:
Cigarette smoking is a major risk factor for atherosclerosis. Endothelial dysfunction is considered to be a key initiating event in the pathogenesis of atherosclerosis. Cigarette smoking induces endothelial dysfunction such as damaging the vasodilatory, antithrombotic and anti-inflammatory functions of endothelia and increasing oxidative stress, thus enhancing atherosclerosis.

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备注/Memo

备注/Memo:
收稿日期：2014-08-05.
通讯作者：刘惠亮，教授，主要从事心血管介入研究 Email:huiliangl531@163.com
作者简介：赖斌，硕士生 Email:bing237732113@qq.com
更新日期/Last Update: 2015-04-22