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|本期目录/Table of Contents|

miRNA与急性心肌梗死

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2016年第1期
页码:
117-119
栏目:
综述
出版日期:
2015-09-15

文章信息/Info

Title:
Research progress of miRNA and myocardial infarction
作者:
黄小凤; 胡昌兴
(广西壮族自治区人民医院心血管内科，广西 南宁 530021）
Author(s):
HUANG Xiao-feng;  HU Chang-xing
(Department of Cardiology, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi, China)
关键词:
miRNA; 急性心肌梗死; 治疗靶点
Keywords:
miRNA;  acute myocardial infarction;  therapeutic target
分类号:
R514
DOI:
-
文献标识码:
A
摘要:
心肌梗死（MI）是心血管疾病导致死亡的最主要原因之一。miRNA是一类非编码小分子RNA。研究证实，MI后miRNA表达异常，通过转录后水平参与MI及其并发症的病理生理过程，有望成为急性心肌梗死(AMI)新的生化标志物和治疗靶点。
Abstract:
Myocardial infarction (MI) is a leading cause of death among all cardiovascular diseases. miRNA is a class of non-coding small RNA. Research confirms that miRNA expression becomes abnormal after MI and miRNA posttranscriptionally controls gene expression. Recent research has unveiled an important impact of miRNA on the pathophysiology of MI and its complications. Determination of miRNA expression levels therefore offers a potential diagnostic value and therapeutic target.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2014-08-15.
作者简介：黄小凤，住院医师，硕士 Email：770516632@qq.com
更新日期/Last Update: 2015-09-16