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|本期目录/Table of Contents|

新疆焉耆县维吾尔族血尿酸水平与高血压水平和动脉硬化严重程度的相关性

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2016年第4期
页码:
460-463
栏目:
临床研究
出版日期:
2016-04-01

文章信息/Info

Title:
Correlation between serum uric acid levels and arterial stiffness in Uygur hypertensive patients
作者:
金 鹏1; 刘 强2; 陈永华2; 陈丽萍2; 李 靖3; 余学江2
(1.中国石油天然气集团公司中心医院心内科，河北 廊坊 065000；
2.新疆巴音郭楞蒙古自治州焉耆县人民医院重症医学科，新疆 焉耆 841000；
3.河北大学附属医院心内科，河北 保定071000)
Author(s):
JIN Peng1;  LIU Qiang2;  CHEN Yong-hua2;  CHEN Li-ping2;  LI Jing3;  YU Xue-jiang2
(1.Department of Cardiology, Central Hospital of China National Petroleum Corporation, Langfang 065000, Hebei, China；
2.ICU, People’s Hospital, Yanqi County, Bayinhe Guo Lengmeng, YanFi 841000, Xinjiang, China；
3.Department of Cardiology, Affiliated Hospital, Hebei University, Baoding 071000, Hebei, China)
关键词:
维吾尔族; 高血压; 原发性; 尿酸; 臂踝脉搏波传导速度; 颈动脉内膜中层厚度
Keywords:
Uygur;  hypertension;  uric acid;  brachial ankle pulse wave velocity;  carotid intima media thickness
分类号:
R544.1
DOI:
-
文献标识码:
A
摘要:
目的 通过回顾性分析新疆焉耆县维吾尔族高血压病患者血尿酸（SUA）水平与高血压水平及SUA水平与臂踝脉搏波传导速度(baPWV)和颈动脉内膜中层厚度（ITM）的相关性。方法 选取2014~2015年在新疆焉耆县人民医院住院的206例高血压病患者，根据SUA水平分为2组:高SUA血症组患者149例，并在该组中根据SUA的二分位数值，将以SUA 466 μmol/L为界限分为两亚组SUA水平<466 μmol/L的A组61例，以及SUA水平≥466 μmol/L的B组88例。并将SUA水平正常者列为对照组共57例。所有患者均于入院时应用同一台全自动动脉硬化测定仪测量baPWV，并由同一名血管超声技师应用同一台超声探头行ITM检测。结果 两组间血压水平对照组与试验组比较，试验组中两亚组比较均有统计学意义(P<0.05)。两组间baPWV和ITM比较，试验组中两亚组比较P<0.05。而相关性分析提示试验组中两亚组血压比较P<0.05，且血压水平与SUA水平相关性分析有相关性，SUA水平与血压水平呈正相关。结论 SUA水平对预测高血压及动脉硬化有重要的意义，且SUA水平越高，其颈动脉的粥样斑块越严重，两者有非常显著的相关性。
Abstract:
AIM To analyze the correlation between serum uric acid (SUA) level, blood pressure, blood uric acid level, brachial-ankle pulse wave velocity (baPWV) and carotid artery intima-media thickness (IMT) in Uygur hypertensive patients in Yanqi County of Xinjiang. METHODSA retrospective analysis was conducted in 206 hospitalized hypertensive patients from 2014-2015 in Yanqi County People's Hospital. According to the level of blood uric acid, patients were divided into hyperuricemia group (experimental group, n=149) and normal SUA group (control group, n=57). The experimental group was subdivided into group A (n=61) with SUA level<466 μmol/L and group B (n=88) with SUA value≥466 μmol/L. baPWV of all patients was measured with the same automatic detector and IMT was probed by the same technician. RESULTSStatistically significant difference was found in blood pressure levels, IMT and baPWV between the experimental group and control group and between the two subgroups in the experimental group (all P<0.05). Correlation analysis showed that blood pressure levels were positively correlated with SUA levels. CONCLUSIONSUA levels are of significance for predicting hypertension and arterial atherosclerosis. Blood pressure levels are positively correlated with SUA levels the higher uric acid levels, the more serious atherosclerotic plaques of the carotid artery.

参考文献/References

[1]李自成，刘 勇，巫少荣，等.应用ROC曲线评价颈总动脉内中膜厚度对冠心病的诊断价值[J].临床心血管病杂志,2004,20(6):337-339.
[2] Bots ML,Hofman A,Grobbee DE.Increased common carotid intima-media thickness: adaptive response or a reflection of atherosclerosis Rotterdam study[J].Stroke,1997,28(12):2442-2447.
[3]李 璞,袁如玉,闫哲慧,等. 高血压患者baPWV与早期肾功能损害及左室肥厚的相关性分析[J].天津医药,2014,42(4):345-348.
[4]韩秀玲,张志纺,沈志霞，等.中国汉族人群原发性高血压危险因素横断面调查[J].中国现代医学杂志,2010,20(23):3607-3610.
[5]王 宁,余振球.高血压患者血压变异性与肱踝脉搏波传导速度的关系研究[J].中国全科医学,2012,15(3):851-853.
[6]中国医师协会心血管内科医师分会,中国医师协会循证医学专业委员会.无症状高尿酸血症合并心血管疾病诊治建议中国专家共识[J].中国当代医药,2009, 16(24):4-8.
[7]陈 静,林靖宇.急性冠状动脉综合征患者肱踝脉搏波传导速度的临床研究[J].中国临床医学, 2015,22(1):93-94.
[8]梁丽艳,陈曦,张源明,等.伴糖耐量异常的原发性高血压患者SUA与颈动脉硬化、动脉僵硬度的相关性研究[J].疑难病杂志,2015,14(3):223-226.

备注/Memo

备注/Memo:
收稿日期：2015-06-17.
通讯作者：余学江，主治医师，主要从事重症医学研究 Email：eagleking123@126.com
作者简介：金鹏,副主任医师，硕士 Email：eagleking123@126.com
更新日期/Last Update: 2016-04-01