红细胞分布宽度与阵发性心房颤动导管射频消融术后复发的关系
《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]
- 期数:
- 2016年第5期
- 页码:
- 542-545,551
- 栏目:
- 临床研究
- 出版日期:
- 2016-04-25
文章信息/Info
- Title:
- Relationship between red cell distribution width and recurrence of paroxysmal atrial fibrillation after radiofrequency catheter ablation
- Author(s):
- ZHAO Pei; LIAN Cheng; LIU Xiong-tao; ZENG Di; YAN Song; WANG Chi-yao; ZHENG Qiang-sun
- (Department of Cardiovascular, Tang Du Hospital of The Forth Military Medical University, Xi’an 710038, Shaanxi, China)
- Keywords:
- red cell distribution width; atrial fibrillation; radiofrequency catheter ablation; recurrence
- 分类号:
- R541.7
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 目的 探讨红细胞分布宽度（RDW）与阵发性心房颤动(简称房颤)导管射频消融术后复发的关系及其相关机制。 方法 连续收集2013年1月~2014年12月在本中心行射频消融治疗的阵发性房颤患者，收集其基线资料并随访其术后复发情况。按照复发与否分为复发组与未复发组，统计分析两组间基线资料、实验室检验指标和超声心动图测定值间的差异， Logistic回归分析差异指标对消融术后复发率的预测价值。结果 共105人纳入研究，随访（8±4）个月，共计复发36例。统计数据表明：两组间基线资料无明显差异，实验室检测指标和超声心动图测定值中仅RDW在复发组显著高于未复发组（P<0.05）。二分类Logistic回归分析显示：RDW是阵发性房颤射频消融术后复发的独立预测因素（OR=2.847，P<0.05）。将RDW采用中值分组后比较示：Q2组较Q1组复发率明显增高（P<0.05），具有统计学意义。进一步分析显示：当RDW(%)取最佳截断值13.25%时，对阵发性心房颤动术后复发的预测灵敏度达64%，特异度为67%。结论 RDW是阵发性房颤患者射频消融术后复发的一项独立预测因素。
- Abstract:
- AIM To explore the relationship between red cell distribution width and the recurrence of paroxysmal atrial fibrillation after radiofrequency catheter ablation (RFCA) in patients with paroxysmal atrial fibrillation (PAF). METHODSBetween January 2013 and December 2014, baseline data were collected in 105 PAF patients along with recurrent problems. Patients were grouped according to recurrence or not. Differences in baseline data, laboratory examination indexes and echocardiographic measurements were compared between groups. Logistic regression analysis difference index was evaluated for prediction of recurrence after ablation. RESULTSThere were no significant differences in baseline data. RDW% in recurrent group was significantly higher than in the non-recurrent group. Multivariate logistic regression analysis showed that RDW was an independent predictor for AF recurrence after radiofrequency catheter ablation. After categorization based on median of RDW(%), we found that the rate of recurrence in Q2 was statistically different than Q1 (P<0.05). Using a cut-off point of 13.25, the preoperative level correlated with the incidence of AF with a sensitivity of 64% and specificity of 67%. CONCLUSIONRDW is an independent predictor for the recurrence of paroxysmal atrial fibrillation after radiofrequency catheter ablation.
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备注/Memo
- 备注/Memo:
- 收稿日期：2015-07-10.
基金项目：国家自然科学基金项目资助（31271039）；国家自然科学基金青年项目资助（31400832）
通讯作者：郑强荪,主任医师，主要从事复杂心律失常研究 Email：tdxznk01@fmmu.edu.cn
作者简介：赵佩，硕士生 Email：qiuxin510@sina.com
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