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|本期目录/Table of Contents|

左心耳封堵术预防心房颤动血栓栓塞单中心经验分析

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2017年第1期
页码:
16-019
栏目:
房颤血栓管理-左心耳封堵术
出版日期:
2016-10-05

文章信息/Info

Title:
Safety and feasibility of left atrial appendage closure device to prevent thrombosis embolism in patients with atrial fibrillation: experience of one center
作者:
樊友启1; 杨 倩2; 王建安1
（浙江大学医学院附属第二医院：1.心内科（心脏中心），2.超声科，浙江 杭州 310009）
Author(s):
FAN You-qi1;  YANG Qian2;  WANG Jian-an1
(1.Department of Cardiology, 2.Ultrasound Department, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang, China)
关键词:
左心耳封堵术; 心房颤动; 血栓栓塞
Keywords:
percutaneous left atrial appendage occlusion;  atrial fibrillation;  thrombosis;  embolism
分类号:
R541.75
DOI:
-
文献标识码:
A
摘要:
目的 对中国心房颤动(atrial fibrillation，AF)患者植入WATCHMAN左心耳封堵系统预防血栓栓塞的可行性和安全性进行单中心经验总结。方法 入选年龄40~90岁的非瓣膜性AF患者，CHADS2-VAS评分≥2分和HAS-BLED评分≥3分，且不愿意长期口服抗凝药物或口服抗凝药物有禁忌证。经股静脉途径，穿刺房间隔，将WATCHMAN左心耳封堵器输送系统置入左心房，植入WATCHMAN左心耳封堵装置至左心耳颈部。结果 入选102例AF患者，年龄(72±9)岁，CHADS2-VAS评分4~7(5.3±1.2)分及HAS-BLED评分3~4(3.4±0.6)分，均成功植入WATCHMAN左心耳封堵系统，手术时间(76±18) min，围手术期及术后2个月随访无出血及栓塞等并发症发生。结论 在AF患者中植入WATCHMAN左心耳封堵器预防血栓栓塞是安全可行的。
Abstract:
AIM One center experience is presented of the safety and feasibility of implanting the WATCHMAN left atrial appendage closure device at the ostium of the left atrial appendage to prevent thrombosis embolism in patients with atrial fibrillation (AF) in China. METHODS Nonvalvular AF patients between 40 and 90 years of age whose CHADS2-VAS score was≥2 and HAS-BLED score was≥3 were selected. Patients did not want to take long-term oral anticoagulant drugs or had contraindications for the use of oral anticoagulant drugs. The WATCHMAN left atrial appendage closure device delivery system was implanted into the ostium of the left atrial appendage. RESULTSThere were 102 AF patients enrolled with an average age of (72±9) years, average CHADS2-VAS score (5.3±1.2) and HAS-BLED score (3.45±0.6). Average procedural time was (76±18) min. All patients were successfully implanted with the WATCHMAN left atrial appendage closure device. Peri-procedure and after 2 months follow-up, no complications such as bleeding and embolism were found. CONCLUSION We demonstrated the safety and feasibility of implantation of the WATCHMAN left atrial appendage closure device at the ostium of the left atrial appendage to prevent thrombosis embolism in Chinese AF patients.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2016-05-30.
通讯作者：王建安，主任医师，主要从事心律失常研究 Email:wang_jian_an@tom.com
作者简介：樊友启，副主任医师，博士 Email:fanyouqi1228@126.com
更新日期/Last Update: 2016-10-09