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Title:: Correlation between cardiac chronotropic function and anxiety

作者:: 鲁艳玲; 刘娟; 刘炜; 代雅琪; 陈芳; (武汉大学人民医院心内科，湖北，武汉 430060)

Author(s):: LU Yan-ling; LIU Juan; LIU Wei; DAI Ya-qi; CHEN Fang; (Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China)

关键词:: 心脏变时功能不良; 运动平板试验; 焦虑; 相关性

Keywords:: cardiac chronotropic function; treadmill exercise test; anxiety; correlation

分类号:: R541.6

DOI:: -

文献标识码:: A

摘要:: 目的探讨心脏变时功能和患者焦虑情绪的相关性。方法随机选取2013年4月~2014年12月在我院行运动平板试验的患者101(男63，女38)例。记录静息时心电图、血压、运动中心率及血压变化、运动时间、运动量mets，监测血压、心率至运动后6 min。分别测量并计算运动后最大心率值、心脏变时性指数和运动结束后心率下降值。并对其进行焦虑自评量表（SAS）的问卷调查。所有数据采用SPSS17.0软件进行分析。结果 101例患者中焦虑39例，非焦虑62例。焦虑组与非焦虑组峰值心率/极量心率、心率储备和心脏变时性指数存在显著性差异；而焦虑相关因素的Logistic回归分析显示峰值心率/极量心率、心脏变时性指数、心率储备和代谢储备与焦虑并无显著性相关；焦虑评分与心脏变时功能相关性分析结果显示焦虑评分与运动时间呈显著性负相关，而与峰值心率/极量心率和心脏变时性指数呈显著性正相关。结论焦虑情绪会通过影响自主神经而影响冠心病患者的心脏变时功能，从而导致心脏变时功能不良假阴性结果的出现。

Abstract:: AIM To explore the correlation between cardiac functions and anxiety and to provide evidence for clinical diagnosis of chronotropic incompetence. METHODSOne hundred and one patients were randomly selected from April 2013 to December 2014 in our hospital, including 63 males and 38 females. ECG, blood pressure, heart rate and blood pressure changes during exercise, exercise time and amount of exercise were recorded. Maximum heart rate, chronotropic response index and decrease of heart rate after exercise were measured and calculated. Self-rating anxiety scale (SAS) was used and all data were analyzed with SPSS 17.0 software. RESULTSAmong the 101 patients, 39 demonstrated anxiety and 62 had no anxiety. A significant difference was found in peak heart rate/maximal heart rate, heart rate reserve and chronotropic response index between anxiety group and nonanxiety group. Logistic regression analysis showed no significant correlation between anxiety and peak heart rate/maximal heart rate, chronotropic response index, heart rate reserve and metabolic reserve. The correlation analysis of anxiety scores and cardiac chronotropic functions showed that anxiety scores and exercise time were negatively correlated but positively correlated with peak heart rate/maximum heart rate and chronotropic response index. CONCLUSIONAnxiety can affect cardiac chronotropic functions in patients with coronary heart disease through its effect on the autonomic nervous system, which will lead to the emergence of false negative results of chronotropic incompetence.

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心脏变时功能与焦虑情绪的相关性

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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