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|本期目录/Table of Contents|

血流储备分数指导下介入治疗冠脉临界病变对NSTE-ACS患者预后的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2017年第3期
页码:
290-292
栏目:
临床研究
出版日期:
2017-01-25

文章信息/Info

Title:
Prognostic effects of fractional flow reserve guided interventional therapy in non-ST elevation acute coronary syndrome patients with borderline lesions
作者:
郭 欣; 刘海涛; 李 飞
第四军医大学第一附属医院心血管内科，陕西 西安 710032
Author(s):
GUO Xin;  LIU Hai-tao;  LI Fei
Department of Cardiology, First Affiliated Hospital, Fourth Military University, Xian 710032, Shaanxi, China
关键词:
血流储备分数; 冠状动脉临界病变; 冠状动脉造影; 主要不良心脏事件
Keywords:
Key words: fractional flow reserve;  borderline coronar
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 观察血流储备分数（fractional flow reserve,FFR）指导下介入治疗冠脉临界病变对非ST段抬高型急性冠脉综合征(NSTE-ACS)患者短期预后的影响。方法 选取西京医院心血管内科冠状动脉造影(CAG)确定单支冠脉狭窄程度为50%~70%且拟行经皮冠状动脉介入(PCI)治疗的192例NSTE-ACS患者为研究对象，按随机数字表将患者分为CAG组(n=96)和FFR组(n=96)，患者随访12个月，比较两组患者再发心绞痛和主要不良心血管事件（MACE）的发生情况。结果 与CAG组比较，FFR组再发心绞痛和MACE事件发生率均显著降低（P<0.05）。结论 FFR指导下PCI治疗冠脉临界病变可更显著降低术后1年MACE事件发生率。
Abstract:
AIM To observe the prognostic effect of fractional flow reserve (FFR) guided interventional therapy in non-ST elevation acute coronary syndrome (NSTE-ACS) patients with borderline lesions. METHODSNS TE-ACS patients with coronary stenosis (50-70% of the lesions) confirmed by coronary artery angiography (CAG) in our hospital were randomly divided into CAG group and FFR group. Patients were followed for 12 months and the rates of recurrent angina pectoris and major adverse cardiovascular events (MACE) were compared between groups. RESULTS The rates of recurrent angina and MACE events in FFR group were lower compared with the CAG group. CONCLUSION FFR guided PCI treatment better alleviates the symptoms of patients with angina pectoris, reduces MACE events and improves the prognosis of patients with NSTE-ACS critical lesions.

参考文献/References

[1]Tobis J,Azarbal B,Slavin L.Assessment of intermediate severity coronary lesions in the catheterization laboratory[J].J Am Coll Cardiol,2007,49(8):839-848.
[2]延荣强，陈纪林.冠状动脉临界病变的有创评价和治疗[J].中国循环杂志,2012,27(2):156-158.
[3]Hamm CW,Bassand JP,Agewall S,et al.ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation:the task force for the management of acute coronary syndromes(ACS)in patients presenting without persistent ST-segment elevation of the European Society of Cardiology(ESC)[J].Eur Heart J,2011,32(23):2999-3054.
[4]中华医学会心血管病学分会介入心脏病学组,中华心血管病杂志编辑委员会.中国经皮冠状动脉介入治疗指南2012[J].中华危重症医学杂志(电子版),2012,5(3):169-180.
[5]Tonino PA,Fearon WF,De Bruyne B,et al.Angiographic versus functional serversity of coronary artery stenosis in FAME study fractional flow reserve versus angiography in multivessel evaluation[J].J Am Coll Cariol,2010,55(25):2816-2821.
[6]Stone GW,Maehara A,Lansky AJ,et al.A prospective Natural-History study of coronary atherosclerosis[J].N Engl J Med,2011,364(3):226-235.
[7]Lansky AJ,Goto K,Cristea E,et al.Clinical and angiographic predictors of short-and long-term ischemic events in acute coronary syndromes:results from the acute catheterization and urgent intervention triage strategy trial[J].Circ Cardiovasc Interv,2010,3(4):308-316.
[8]Pijls NH,van Schaardenburgh P,Manoharan G,et al.Percutaneous coronary intervention of functionally nonsignificant stenosis:5 years follow-up of the DEFER study[J].J Am Coll Cariol,2007,49(21):2105-2111.
[9]韩战营，陈晓杰，卢文杰，等.冠状动脉血流储备分数≥0.75在冠状动脉临界病变药物治疗的长期临床疗效及影响因素分析[J].临床心血管病杂志,2013,29(11):849-852.

备注/Memo

备注/Memo:
收稿日期：2016-04-27.通讯作者：李飞，副教授，主要从事冠心病基础和临床研究 Email:lifei01@fmmu.edu.cn 作者简介：郭欣，主治医师，硕士生 Email: guoxin0537@163.com
更新日期/Last Update: 2017-02-20