我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

主动固定电极在右心室不同部位起搏损伤电流变化(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2017年第4期
页码:
452-454,459
栏目:
临床研究
出版日期:
2017-02-25

文章信息/Info

Title:
Changes of current of injury after active fixation lead in different sites of right ventricular pacing
作者:
杨 军; 金 艳; 陈 英; 黄 强; 徐 欣; 曹佳宁; 杨承健
无锡市第二人民医院心内科，江苏 无锡 214002
Author(s):
YANG Jun;  JIN Yan;  CHEN Ying;  HUANG Qiang;  XU Xin;  CAO Jia-ning;  YANG Cheng-jian
Department of Cardiology, Wuxi Second Hospital, Nanjing Medical University, Wuxi 214002, Jiangsu, China
关键词:
主动固定电极; 右心室起搏; 损伤电流
Keywords:
active fixed lead;  right ventricular pacing;  current of injury
分类号:
R541.7
DOI:
-
文献标识码:
A
摘要:
目的 探讨主动固定电极植入右心室心尖部及中位间隔部后损伤电流（current of injury，COI）的变化特点。方法 入选88例右心室植入主动固定电极患者，分为右心室心尖组及中位间隔组。测定电极螺旋旋出0、5、10 min的COI及常规起搏参数，分析COI变化特点及相关关系。结果 88例患者中有2例因心腔内电图（intracardiac electrogram,ICEG）振幅过大，其产生的COI无法准确测量。剩余86例患者测定的COI在主动固定电极螺旋旋出后逐步降低，5 min测定COI与0 min相比下降〔(6.6±1.5) mV vs.(7.6±1.7) mV,P<0.05〕，10 min测定COI与5 min相比显著下降〔(5.5±1.5) mV vs.(6.6±1.5) mV，P<0.05〕;螺旋旋出10 min后较0 min显著降低（P<0.01）。右心室主动固定电极测定的COI在心尖组及中位间隔组的差异无统计学意义。Pearson相关分析发现，0 min测定COI与起搏阈值之间呈负相关，相关系数(r)=-0.497,P<0.01。术后2例患者电极脱位，其COI均<5.0 mV。结论 右心室主动固定电极螺旋旋出后COI值逐步降低，心尖组与中位间隔组COI的差异无统计学意义。0 min测定COI与起搏阈值之间呈负相关。
Abstract:
AIM To investigate changes of current of injury (COI) after active fixation lead in apex and median septum of right ventricular pacing. METHODSE ighty-eight patients with active fixation lead implanted in the right ventricle were divided into right ventricular apex group and median septum group. We determined COI at 0 min, 5 min and 10 min after lead fixation and conventional pacing parameters, and analyzed the correlation between COI and conventional pacing parameters. RESULTS In our 88 patients, COI could not be accurately measured in 2 patients due to the large amplitude of intracardiac electrogram (ICEG). In the remaining 86 cases, COI gradually reduced with the passage of time after lead fixation. COI was determined at 5 min after lead fixation decreased compared with that was determined at 0 min ［(6.6±1.5) mV vs.(7.6±1.7) mV, P<0.05］, COI at 10 min decreased compared with that at 5 min ［(5.5±1.5) mV vs.(6.6±1.5) mV, P<0.05］, and COI was determined at 10min decreased significantly compared with that at 0 min (P<0.01). But no statistical difference was found in COI of right ventricular active fixation lead between apex group and median interval group (P>0.05). Pearson correlation analysis showed an inverse correlation between COI measured at 0 min and the pacing threshold (correlation coefficient: -0.497, P<0.01). COI of the 2 patients with postoperatively dislocated lead was less than 5.0 mV. CONCLUSION COI of right ventricular active fixation lead gradually reduces with the passage of time after lead fixation and no statistical difference has been found between implantation in apex and median septum. COI measured at 0 min is inversely correlated with the pacing threshold.

参考文献/References

[1]DeCaprio V,Hurzeler P,Furman S. A comparison of unipolar and bipolar electrograms for cardiac pacemaker sensing[J].Circulation,1977,56(5):750-755.
[2]Myers GH,Kresh YM,Parsonnet V.Characteristics of intracardiac electrograms[J].Pacing Clin Electmphysiol,1978,1(1):90-103.
[3]Redfearn DP,Gula LJ,Krahn AD,et al.Current of injury predicts acute performance of catheter-delivered active fixation pacing leads[J].Pacing Clin Elecirophysiol,2007,30(12):1438-1444.
[4]Saxonhouse SJ,Conti JB,Curtis AB.Current of injury predicts adequate active lead fixation in permanent pacemaker/defibrillation leads[J].J Am Coll Cardiol,2005,45(3):412-417.
[5]沙来买提·沙力,宿燕岗,徐勋龙,等.不同起搏导线植入术中的损伤电流特征[J].中华心律失常学杂志,2013,17(6):431-434.
[6]Myers GH,Kresh YM,Parsonnet V.Characteristics of intracardiac electrograms[J].Pacing Clin Electrophysiol,1978,1(11):90-103.
[7]何 浪,沈法荣,金红峰,等.室间隔起搏损伤电流的临床应用研究[J].中华心律失常学杂志,2012,16(2):131-133.

备注/Memo

备注/Memo:
收稿日期：2016-08-30.作者简介：杨军，主治医师，在职博士生 Email:yangjun821102@126.com
更新日期/Last Update: 1900-01-01