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《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:

2017年第5期

页码:

570-573

栏目:

临床研究

出版日期:

2017-03-25

文章信息/Info

Title:

Influence of healthy lifestyle on prognosis of patients undergoing elective percutaneous coronary intervention

作者:

李 超¹; 2; 李 毅²; 李 晶²; 孙 毅²; 齐 静²; 王贺阳²; 许晓明¹; 2; 韩雅玲²; 陶 凌¹

(1.第四军医大学西京医院心血管内科，陕西 西安 710032；
2.沈阳军区总医院心血管内科，辽宁 沈阳 110016)

Author(s):

LI Chao¹; 2;  LI Yi²;  LI Jing²;  SUN Yi²;  QI Jing²;  WANG He-yang²;  XU Xiao-ming¹; 2;  HAN Ya-ling²;  TAO Ling¹

(1.Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, Shaanxi, China；
2.Department of Cardiology, General Hospital, Shenyang Military Command, Shenyang 110016, Liaoning, China)

关键词:

生活方式; 急性冠脉综合征; 经皮冠状动脉介入治疗

Keywords:

lifestyle;  acute coronary syndrome;  percutaneous coronary intervention

分类号:

R541.4

DOI:

-

文献标识码:

A

摘要:

目的 调查健康的生活方式对急性冠脉综合征(ACS)患者择期经皮冠状动脉介入（PCI）治疗预后的影响。方法 选取出院患者2276例，对其中诊断为ACS并择期行PCI术的患者1 159例随访1年，最终纳入1 129例（其中3例在随访过程中排除，27例失访），按是否有健康的生活方式分为健康生活方式组（戒烟、合理饍食和运动康复至少占一项，n=294）与对照组（n=835），比较两组患者主要心脑血管不良事件（MACCE）和术后心绞痛的发生率。结果 纳入的1 129例患者中，仅294例患者（26.0%）至少坚持了或改善为一种良好的生活方式，其中230例患者选择了戒烟，占本组78.2%，112例患者重视了良好的饮食习惯，占本组38.1%，118例患者坚持了运动康复，占本组40.1%,约2/5患者具有2项或3项健康生活方式。健康生活方式组MACCE事件总发生率（9.9%）显著低于对照组（15.1%），差异有统计学意义(P<0.05),单因素分析影响预后的因素包括：健康的生活方式、城市居民、左室射血分数是保护性因素；高脂血症、植入支架数、最大狭窄率是危险因素，利用可能影响患者预后的因素作为因子多元逐步Cox比例风险回归模型模型分析结果是危险比(hazard ratio,HR)=0.642，95%可信区间0.429~0.962，P<0.05。结论 健康生活方式能够显著降低1年期MACCE事件的发生率。

Abstract:

AIM To investigate the effect of healthy lifestyle on the prognosis of elective percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS). METHODS 2 276 cardiovascular patients were selected in Xijing Hospital of which 1 129 cases were diagnosed as ACS and undergoing PCI, divided into healthy lifestyle group (n=294) and control group (n=835) by whether his or her lifestyle is healthy, compared two groups of patients with main adverse cardiovascular and cerebrovascular events（MACCE）and the angina events. RESULTS Of the 1 129 patients enrolled, only 294 patients (26.0%) improve or adhere to at least one good lifestyle, among which 230 patients chose to quit smoking, 78.2% of the group, 112 cases of patients focus on good eating habits, 38.1% of the group, 118 patients adhere to the movement recovery. The rate of MACCE (9.9%) in the healthy lifestyle group was significantly lower than that in the control group (15.1%), and the difference was statistically significant (P<0.05). CONCLUSION Healthy lifestyle can significantly reduce the occurrence of MACCE in one year.

参考文献/References

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备注/Memo

备注/Memo:

收稿日期：2016-12-20.
通讯作者：陶凌，教授，主要从事糖尿病心肌损伤研究 Email：lingtao@fmmu.edu.cn 共同
通讯作者：韩雅玲，教授，主要从事冠心病的诊断与治疗研究 Email：hanyaling@263.net
作者简介：李超，主治医师，硕士 Email：lichao19811228@sina.com

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更新日期/Last Update: 2017-04-20