我们的网站为什么显示成这样?

可能因为您的浏览器不支持样式,您可以更新您的浏览器到最新版本,以获取对此功能的支持,访问下面的网站,获取关于浏览器的信息:

|本期目录/Table of Contents|

二尖瓣成形环瓣环环缩术在缺血性二尖瓣返流中的应用

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2017年第6期
页码:
710-713,716
栏目:
临床研究
出版日期:
2017-06-01

文章信息/Info

Title:
Mitral annuloplasty with prosthetic ring in ischemic mitral regurgitation
作者:
仲肇基刘 盛凤 玮孙寒松许建屏吕 锋王水云尹朝华
(中国医学科学院阜外医院心外科,北京 100037)
Author(s):
ZHONG Zhao-ji LIU Sheng FENG Wei SUN Han-song XU Jian-ping L Feng WANG Shui-yun YIN Zhao-hua
(Department of Cardiovascular Surgery, Fuwai Hospital, Chinese Academy of Medical Science, Beijing 100037, China)
关键词:
二尖瓣成形术缺血性二尖瓣返流二尖瓣瓣环成形
Keywords:
mitral valvuloplasty ischemic mitral regurgitation mitral valve annuloplasty
分类号:
R542.5
DOI:
-
文献标识码:
A
摘要:
目的 研究应用二尖瓣成形环行瓣环环缩术治疗缺血性二尖瓣返流的手术效果。方法 选择2000年1月~2015年12月在我院行二尖瓣成形术的缺血性二尖瓣返流并发室壁瘤的患者72例,根据二尖瓣病变部位及性质选择成形方案,其中33例使用二尖瓣成形环进行瓣环环缩术。回顾性分析手术的近期、远期治疗效果。结果 围手术期死亡4例(6%)。术后二尖瓣返流程度较术前明显改善,中度及中度以上二尖瓣返流1例(1%)。术后随访(5±3)年,随访期死亡11例(16%),出现中度及中度以上二尖瓣返流12例(18%)。是否使用成形环进行瓣环环缩术后早期二尖瓣返流程度无统计学差异,但远期成形环环缩组较对照组二尖瓣返流程度有显著改善(P<0.05)。结论 缺血性二尖瓣返流并发室壁瘤的患者中,二尖瓣成形术可安全、有效地重建二尖瓣功能。使用成形环进行瓣环环缩可改善远期效果。
Abstract:
AIM The investigation studied the investigate the outcomes of mitral annuloplasty with prosthetic rings in patients with ischemic mitral regurgitation (IMR) and ventricular aneurysm. METHODS Seventy-two patients with IMR and ventricular aneurysm who underwent mitral valve repair and ventricular aneurysm restoration were enrolled and 33 of them underwent mitral annuloplasty with prosthetic rings. The surgical and long-term outcomes of the patients were analyzed. RESULTS Surgical mortality was 6% and mitral regurgitation was significantly corrected after surgery. During follow-up, moderate or above moderate mitral regurgitation was observed in 18% of the patients. Although the use of mitral annuloplasty ring led to prolonged cardiopulmonary bypass time and cross-clamp time, it alleviated the long-term mitral valve regurgitation. CONCLUSION In patients with IMR and ventricular aneurysm, mitral valve repair is feasible and safe in reconstructing mitral valve function. The use of mitral annuloplasty ring could potentially alleviate long-term mitral valve regurgitation.

参考文献/References

[1]Jensen H,Jensen MO,Nielsen SL.Surgical Treatment of Functional Ischemic Mitral Regurgitation[J].J Heart Valve Dis,2015,24(1):30-42.
[2]Mozaffarian D,Benjamin EJ,Go AS,et al.Heart disease and stroke statistics--2015 update:a report from the American Heart Association[J].Circulation,2015,131(4):e29-e322.
[3]Grigioni F,Enriquez-Sarano M,Zehr KJ,et al.Ischemic mitral regurgitation: long-term outcome and prognostic implications with quantitative Doppler assessmen[J].Circulation,2001,103(13):1759-1764.
[4]Levine RA,Schwammenthal E.Ischemic mitral regurgitation on the threshold of a solution: from paradoxes to unifying concepts[J].Circulation,2005,112(5):745-758.
[5]Mihos CG,Santana O.Mitral valve repair for ischemic mitral regurgitation:lessons from the Cardiothoracic Surgical Trials Network randomized study[J].J Thorac Dis,2016,8(1):E94-E99.
[6]Smith PK,Puskas JD,Ascheim DD,et al.Surgical treatment of moderate ischemic mitral regurgitation[J].N Engl J Med,2014,371(23):2178-2188.
[7]Madesis A,Tsakiridis K,Zarogoulidis P,et al.Review of mitral valve insufficiency:repair or replacement[J].J Thorac Dis,2014,6( Suppl 1):S39-S51.
[8]Acker MA,Parides MK,Perrault LP,et al.Mitral-valve repair versus replacement for severe ischemic mitral regurgitation[J].N Engl J Med,2014,370(1):23-32.
[9]Santana O,Lamelas J.Surgical options of ischemic mitral regurgitation[J].Cardiol Rev,2010,18(4):163-170.
[10]De Bonis M,Lapenna E,Verzini A,et al.Recurrence of mitral regurgitation parallels the absence of left ventricular reverse remodeling after mitral repair in advanced dilated cardiomyopathy[J].Ann Thorac Surg,2008, 85(3):932-939.
[11]Crabtree TD,Bailey MS,Moon MR,et al.Recurrent mitral regurgitation and risk factors for early and late mortality after mitral valve repair for functional ischemic mitral regurgitation[J].Ann Thorac Surg,2008,85(5):1537-1542,1542-1543.
[12]Mihos CG,Pineda AM,Santana O.Targeting the Papillary Muscles in Mitral Valve Repair for Ischemic Mitral Regurgitation[J].Rev Cardiovasc Med,2015,16(3):182-188.
[13]Kato Y,Bando K,Fukui T,et al.Surgical treatment of functional mitral regurgitation involving the subvalvular apparatus[J].J Card Surg,2015,30(1):27-34.
[14]Wagner CE,Kron IL.Subvalvular techniques to optimize surgical repair of ischemic mitral regurgitation[J].Curr Opin Cardiol,2014,29(2):140-144.
[15]Hung J,Solis J,Handschumacher MD,et al.Persistence of mitral regurgitation following ring annuloplasty:is the papillary muscle outside or inside the ring?[J].J Heart Valve Dis,2012,21(2):218-224.
[16]Mcgee EC,Gillinov AM,Blackstone EH,et al.Recurrent mitral regurgitation after annuloplasty for functional ischemic mitral regurgitation[J].J Thorac Cardiovasc Surg,2004,128(6):916-924.
[17]Mihos CG,Santana O,Lamelas J.Transventricular edge-to-edge repair of the mitral valve during surgical ventricular restoration:review of the literature[J].J Card Surg,2012,27(1):52-55.
[18]Zoghbi WA,Enriquez-Sarano M,Foster E,et al.Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and Doppler echocardiography[J].J Am Soc Echocardiogr,2003,16(7):777-802.
[19]Castleberry AW,Williams JB,Daneshmand MA,et al.Surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation:a 20-year experience[J].Circulation,2014,129(24):2547-2556.
[20]Velazquez EJ,Lee KL,Deja MA,et al.Coronary-artery bypass surgery in patients with left ventricular dysfunction[J].N Engl J Med,2011,364(17):1607-1616.
[21]Nishimura RA,Otto CM,Bonow RO,et al.2014 AHA/ACC guideline for the management of patients with valvular heart disease:executive summary:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines[J].J Am Coll Cardiol,2014,63(22):2438-2488.
[22]Vahanian A,Alfieri O,Andreotti F,et al.Guidelines on the management of valvular heart disease(version 2012)[J].Eur Heart J,2012,33(19):2451-2496.
[23]Klein P,Braun J,Holman ER,et al.Management of mitral regurgitation during left ventricular reconstruction for ischemic heart failure[J].Eur J Cardiothorac Surg,2012,41(1):74-80, 80-81.
[24]Suma H,Tanabe H,Uejima T,et al.Surgical ventricular restoration combined with mitral valve procedure for endstage ischemic cardiomyopathy[J].ur J Cardiothorac Surg,2009,36(2):280-284,284-285.
[25]Little SH,Ben ZS,Lawrie GM,et al.Dynamic annular geometry and function in patients with mitral regurgitation:insight from three-dimensional annular tracking[J].J Am Soc Echocardiogr,2010,23(8):872-879.
[26]Daimon M,Saracino G,Fukuda S,et al.Dynamic change of mitral annular geometry and motion in ischemic mitral regurgitation assessed by a computerized 3D echo method[J].Echocardiography,2010,27(9):1069-1077.
[27]Rausch MK,Bothe W,Kvitting JP,et al.Characterization of mitral valve annular dynamics in the beating heart[J].Ann Biomed Eng,2011,39(6):1690-1702.
[28]Mihos CG,Santana O.Is an adjunctive subvalvular repair during mitral annuloplasty for secondary mitral regurgitation effective in preventing recurrent regurgitation?[J].Interact Cardiovasc Thorac Surg,2016,22(2):216-221.

备注/Memo

备注/Memo:
收稿日期:2016-08-05.
通讯作者:尹朝华,副主任医师,主要从事心血管外科临床研究 Email:yinzhaohua@fuwai.com
作者简介:仲肇基,主治医师,博士 Email:zhongzhaoji@sina.com
更新日期/Last Update: 2017-06-06