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应用时间-空间相关成像技术评估妊娠期高血压疾病胎儿心功能

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2018年第1期
页码:
81-084
栏目:
临床研究
出版日期:
2017-10-10

文章信息/Info

Title:
Evaluation of fetal ventricular volume and systolic function in gestational hypertensive states by spatiotemporal image correlation
作者:
杨丽玲1; 姜志荣2; 苏 虹1
(1.青岛市第八人民医院超声科，山东 青岛 266061；2.青岛大学医学院附属医院特检科，山东 青岛 266061)
Author(s):
YANG Li-ling1;  JIANG Zhi-rong2;  SU Hong1
(1.Department of Ultrasonography, Qingdao Eighth People’s Hospital, Qingdao 266061, Shandong, China; 2.Department of Especial Examine, Affiliated Hospital, Qingdao University, Qingdao 266061, Shandong, China)
关键词:
时间-空间相关成像技术; 妊娠期高血压; 胎儿; 心室容量; 心功能
Keywords:
spatio-temporal image correlation;  gestational hypertensive state;  fetal ventricular volume;  systolic function
分类号:
R714.24
DOI:
-
文献标识码:
A
摘要:
目的 探讨时间-空间相关成像(spatio-temporal image correlation,STIC)技术评价妊娠期高血压疾病胎儿心功能的临床应用。方法 运用STIC技术采集110例正常孕妇胎儿及84例妊娠期高血压疾病（PIH）孕妇胎儿心动周期图像，通过VOCAL功能获得容积参数，包括左、右心室舒张末期容积（LVEDV、RVEDV），左、右心室收缩末期容积（LVESV、RVESV），计算出左、右心室每搏量（LVSV、RVSV），左、右心室射血分数（LVEF、RVEF），左、右心室心排出量（LVCO、RVCO）。根据孕妇高血压严重程度及临床症状分为：PIH I组(孕妇血压轻度升高或轻度子痫前期):即孕妇妊娠20周后第1次出现血压升高，140/90 mmHg≤血压值<160/110 mmHg(1 mmHg=0.133 kPa),间隔6 h以上，至少出现过两次,尿蛋白弱阳性；PIH II组(重度子痫前期):血压≥160/110 mmHg，和(或)尿蛋白阳性或者强阳性(++),或伴有微血管溶血、神经系统及肺水肿等症状。结果 ①与对照组相比，PIH I组胎儿左、右EDV、ESV、SV、EF、CO差异均无统计学意义；②与对照组、PIH I组相比，PIH II组胎儿的左、右EDV、ESV增大、差异有统计学意义（P<0.05，P<0.01），PIH II组胎儿的SV、EF、CO均减小，差异有统计学意义（P<0.05，P<0.01）。结论 STIC技术可以评价妊娠期高血压病胎儿心功能的变化。
Abstract:
AIM To investigate the value of Spatio-temporal Image Correlation (STIC) technique in evaluating fetal ventricular volume and systolic function in pregnancy induced hypertensive states, (PIH). METHODS Fetal heart ventricular volumes were measured using a STIC technique in 84 women with PIH (PIH group) and 110 women with normal pregnancy (normal group). The virtual organ computer-aided analysis (VOCAL) technique was used to obtain systolic and diastolic ventricular volumes. The stroke volume (SV), ejection fraction (EF) and cardiac output (CO) were calculated. Patients with gestational hypertensive states were divided into two groups: PIH I group: the mothers with the hypertensive states and the mildly pre-eclamptic were devided into a PIH I group whose blood pressure after 20 weeks of pregnancy was higher than 140/90 mmHg , was less than 160/110 mmHg and measured once every 6 hours, more than two times and whose proteinuria was negative; PIH II group: The mothers with severe pre-eclampsia were devided into PIH II group whose blood pressure was higher than 160/110 mmHg and whose proteinuria was positive. RESULTS When compared with normal group, the systolic and diastolic ventricular volumes, stroke volume (LVSV, RVSV)， ejection fraction (LVEF, RVEF) and cardiac output (LVCO, RVCO) of the PIH I group were significantly different. When compared with normal and the PIH I group, the systolic and diastolic ventricular volumes of the PIH II group were higher (P<0.05, P<0.01). The stroke volume (SV), ejection fraction (EF) and cardiac output (CO) of PIH II group were decreased (P<0.05, P<0.01). CONCLUSION SSTIC is an adaptable, reliable, and noninvasive investigative tool for fetal ventricular volume in gestational hypertensive states.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2016-12-05.通讯作者：姜志荣，主任医师，主要从事心脏超声影像的诊断 Email：jiangzhirong2@163.com 作者简介：杨丽玲，主治医师，硕士 Email：haixing911@126.com
更新日期/Last Update: 1900-01-01