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|本期目录/Table of Contents|

心肌细胞活性氧产生途径

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2018年第2期
页码:
240-243
栏目:
综述
出版日期:
2018-02-15

文章信息/Info

Title:
Reactive oxygen species production in cardiomyocytes
作者:
黄章泷1; 2; 雷 霆2; 常 宇1
（1.北京工业大学生命科学与生物工程学院，北京 100124；2.北京深迈瑞医疗电子技术研究院有限公司，北京 100085）
Author(s):
HUANG Zhang-long1; 2;  LEI Ting2;  CHANG Yu1; 2
(1.College of Life Science and Bio-engineering, Beijing University of Technology, Beijing 100124, China; 2.Beijing Shen Mindray Medical Electronics Technology Co., LTD, Beijing 100085, China)
关键词:
心肌细胞; 活性氧; 线粒体; 电子传递链
Keywords:
Heart;  reactive oxygen species;  mitochondria;  electron transfer chain
分类号:
R329.2
DOI:
-
文献标识码:
A
摘要:
活性氧簇（ROS）是一类含氧的自由基或者非自由基分子，具有非常高的生物化学反应活性，能够与生物体内的蛋白质、脂质和DNA发生反应。ROS在正常的生理功能和心脏疾病的发生中均扮演着重要的角色，因此了解心肌细胞ROS的产生对心脏研究有积极意义。本文将综述心肌细胞ROS产生的位点及途径。
Abstract:
Reactive oxygen species (ROS) are a class of oxygen-containing free radicals or non radical molecules, which are so highly reactive that they can react with proteins, lipids and DNA in organisms. ROS play pivotal roles in the heart under both physiological and pathophysiological conditions, so understanding the production process of reactive oxygen species in cardiac cells is important to cardiac research. This review summarizes main ROS production pathways in cardiomyocytes.

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备注/Memo

备注/Memo:
收稿日期：2016-12-19.基金项目：国家自然科技基金项目资助（91430215） 通讯作者：常宇，教授，主要从事人工心脏和心血管方面的研究 Email:changyu@bjut.edu.cn 作者简介：黄章泷，博士后 Email:bio_hzl@126.com
更新日期/Last Update: 1900-01-01