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|本期目录/Table of Contents|

平板运动对青年男性外周血细胞和心功能的影响

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2018年第5期
页码:
566-570
栏目:
临床研究
出版日期:
2018-06-25

文章信息/Info

Title:
Effects of treadmill exercise on peripheral blood cells and heart functions in young males
作者:
石亚君; 王晋丽; 陈韵岱; 郜 玲; 薛 浩
(解放军总医院心血管内科，北京 100853)
Author(s):
SHI Ya-jun;  WANG Jin-li;  CHEN Yun-dai;  GAO Ling;  XUE Hao
(Department of Cardiology, PLA General Hospital, Beijing 100853, China)
关键词:
运动; 心功能; 血细胞; 炎症
Keywords:
exercise;  cardiac function;  blood cells;  inflammation
分类号:
R339.4
DOI:
-
文献标识码:
A
摘要:
目的 研究青年男性一次平板运动对外周血细胞和心功能的影响。方法 筛选健康青年男性21例，采用Bruce方案行平板运动试验，以次级量目标心率（220-年龄）×90%为终点。运动前1 h和结束即刻接受采血和超声心动图检查，并对比两组数据。结果 ①运动结束即刻代表左心室收缩功能参数较运动前增高：左室射血分数（LVEF）［（65±4）% vs.（59±6）%，P<0.01］，和左室短轴缩短率（FS）［（33.1±3.4）% vs.（29.1±2.7）%，P<0.01］；每搏输出量（SV）未见显著变化。运动结束即刻左室舒张功能（E/A,PVS/PVD）较运动前轻度减低［（1.0±0.2）vs.（1.5±0.3），P<0.01；（1.2±0.1）vs.（1.7±0.4），P<0.01］，运动结束即刻，室间隔和下壁在收缩和舒张期均出现组织运动增加［室间隔（0.15±0.03）m/s vs.（0.12±0.02）m/s，P<0.05；（0.17±0.04）m/s vs.（0.13±0.02）m/s，P<0.01；下壁（0.13±0.03）m/s vs.（0.12±0.02）m/s，P<0.01；（0.22±0.12）m/s vs.（0.15±0.03）m/s，P<0.01］，而侧壁主要在舒张期出现运动轻度增加［（0.19±0.05）m/s vs.（0.15±0.02）m/s，P<0.01］。运动结束即刻左右心房内径略减小，左房收缩功能（A峰值和PVA/PVA-t）轻度增加［（0.7±0.1）m/s vs.（0.6±0.1）m/s，P<0.01；（0.3±0.08）vs.（0.3±0.04），P<0.01］。②运动结束即刻较运动前，血液淋巴细胞轻度增加，而中性粒细胞轻度减少［（0.43±0.09）109/L vs.（0.35±0.10）109/L，P<0.01；（0.50±0.09）109/L vs.（0.57±0.10）109/L，P<0.01］，平均血小板体积测定、血小板计数及血小板比积测定均增高［（10.7±0.6）fl vs. （10.6±0.7）fl，P<0.05；（234±43）109/L vs.（214±47）109/L，P<0.01；（0.25±0.04）fl vs.（0.22±0.04）fl，P<0.01］，红细胞体积略微增大［（90.3±2.7）fl vs.（89.8±2.5）fl，P<0.05］。结论 急性运动可以引起心脏收缩功能代偿性的增加，室壁运动增加，代偿性的红细胞体积的增加，血小板的增加和白细胞分类的变化。
Abstract:
AIM To study the effects of treadmill exercise on peripheral blood cells and cardiac function in young males. METHODS Twenty-one healthy young men were screened. A treadmill exercise test was performed with Bruce protocol. The secondary target heart rate (220-age)×90% was used as the endpoint. Routine blood tests and echocardiography were performed 1 hour before and immediately after the exercise. RESULTS Left ventricular systolic function parameters increased immediately after exercise: EF ［(65±4)% vs.(59±6)%, P<0.01］, and FS ［(33.1±3.4)% vs.(29.1±2.7)%, P<0.01］. There were no significant changes in stroke volume (SV). The left ventricular diastolic function (E/A, PVS/PVD) after exercise was slightly lower than that before exercise ［(1.0±0.2) vs.(1.5±0.3), P<0.01, (1.2±0.1) vs.(1.7±0.4), P<0.01］. Immediately after exercise, the interventricular septum (IVS) and inferior wall showed an increase in tissue movement during systole and diastole ［IVS (0.15±0.03) m/s vs.(0.12±0.02) m/s, P<0.05, (0.17±0.04) m/s vs.(0.13±0.02) m/s, P<0.01; inferior wall (0.13±0.03) m/s vs.(0.12±0.02) m/s, P<0.01, (0.22±0.12) m/s vs.(0.15±0.03) m/s, P<0.01］, while the lateral wall increased slightly during diastole ［(0.19±0.05) m/s vs.(0.15±0.02) m/s, P<0.01］. The atrial systolic function (A peak and PVA/PVA-t) slightly increased after exercise ［(0.7±0.1) m/s vs.(0.6±0.1) m/s, P<0.01, (0.3 ±0.08) vs.(0.3±0.04), P<0.01］. The lymphocytes increased mildly and neutrophil granulocytes decreased slightly at the end of exercise ［(0.43±0.09)109/L vs.(0.35±0.10) 109 /L, P<0.01; (0.50±0.09) 109/L vs.(0.57±0.10) 109/L, P<0.01］. The mean platelet volume, platelets count and platelet increased ［(10.7±0.6) fl vs.(10.6±0.7) fl, P<0.05; (234.3±42.9) 109/L vs.(214±47) 109/L, P<0.01; (0.25±0.04) fl vs.(0.22±0.04) fl, P<0.01］. The volume of erythrocytes slightly increased ［(90.3±2.7) fl vs.(89.8±2.5) fl, P<0.05］. CONCLUSION Acute exercise can cause compensatory increases of cardiac systolic function. The wall movement was mainly increased in the inferior wall. After exercise, mean erythrocytes volume was increased compensatorily. Additionally, lymphocytes and platelets were increased, which may be associated with secondary cardiovascular events.

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备注/Memo

备注/Memo:
收稿日期：2017-02-23.基金项目：军队重点课题项目资助（BWS16C005） 通讯作者：陈韵岱，教授，主要从事心血管疾病的研究院 Email：cyundai@vip.163.com 作者简介：石亚君，副主任技师，硕士 Email：shiyajun301@163.com
更新日期/Last Update: 1900-01-01