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《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:

1990年第2期

页码:

82-87

栏目:

论著

出版日期:

1990-02-27

文章信息/Info

Title:

Effects of Furyl-dihydropyridines I on Postischemic Reperfusion Damage in Isolated Rabbit Hearts

作者:

-

Author(s):

Liu Deqiang; Zhao Dehua; Sheng Baoheng

Department of Pharmacology，Fourth Militry Medical University，Xian 710032，China

关键词:

-

Keywords:

furyl-dihydropyridines I; calcium channel blocker; myocardium; ischemia; arrhythmia; enzyme; calcium; sodium; potassium; 1ipid peroxides

分类号:

-

DOI:

-

文献标识码:

-

摘要:

-

Abstract:

In the isolated rabbit heart of recirculating nonpulsatile perfusion circuit，furyl-dihydropyridines I 20μmol／L greatly reduced the leakage of myocardial enzymes and the concentration of ma1ondia1dehyden(MDA)in plasma，decreased the myocardial calcium and

参考文献/References

［1］Robert GT，Margaret PM．J Cardiovasc Pharmaco1 1989；14：560.

［2］Becker LC，Ambeosion G．Prog Cardiovasc Dis 1987；30：23.

［3］Manning A．J MOl Cell Cardiol 1986；18(supp l4)：49.

［4］Liu DQ，Zhao DH，Sheng BH.J Fourth Military Med Univ 1990；11(supp1).

［5］Hou D，Liu WY，Fang FZ，et al.Perfusion 1988；3：205.

[6]Li YL，Fu SX，Li YS． Acta Pharmacol Sin 1989；10：31O.

[7]Edward J，Lensnefsky，Karyl M．J Cardiovasc Pharmacol 1989；13：895.

[8]Lewis BS.Ganz W，Laramce P，et a1.Am Jcardiol 1988；62：20.

[9]McCord JM.N Engl J Med 1985；321：159.

[10]Tosake A，Hearse DJ.Am J Physiol 1987；253：225.

[11]Lakatta EG，Nayler WC，Pvle-wilson PA.Eur J Cardiol 1979；10：77.

[12] Kuroda H，Ishiguro S，Mori I.J Mo1 Cell Cardiol 1986；18：625.

[13] Pidjian AK，Levitsky S，Krukenkamp IB，Silverman N，et al．Thorac Cardiovasc Surg 987；93:128.

[14]Chapman RA，Rodrigo GC,Tunstall J,et al.Am J Physiol 1984；247：H874.

［15］Tang CS，Li ZP，Qi M, et al. J Beijing Med Univ 1987；19：299.

备注/Memo

备注/Memo:

收稿1990年4月

常用功能

更新日期/Last Update: 1990-02-27