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|本期目录/Table of Contents|

高血压病患者的心功能评价(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1996年第3期
页码:
153-156
栏目:
论著
出版日期:
1996-05-01

文章信息/Info

Title:
Assessment of cardiac function in hypertension
作者:
张美芳1 俞 锋2 楼福庆1 秦光明2
浙江医科大学 1心脑血管病研究所 2附属第二医院 杭州 310009
Author(s):
Zhang Meifang1 Yu Feng2 Lou Fuqing1 Qin Guangming2
1Cardiocerebrovascular Institute, 2Second Affiliated Hospital, Zhejiang Medical University, Hangzhou 310009
关键词:
高血压 心脏功能试验
Keywords:
hypertension heart function tests
分类号:
-
DOI:
-
文献标识码:
-
摘要:
应用无创左右心功能同步检测仪测定原发性高血压患者234例的心功能参数与40例正常人比较。结果显示心肌缺血阈值下降; 左室射血分数、左室舒张末期压力、肺毛细血管平均嵌楔压、心肌耗氧量、左室舒张末期血量、左室射血阻抗和动脉弹性模量等较对照组升高(P<0.01)。原发性高血压的心脏早期病变主要表现为左室舒张功能障碍(35% ) , 其受损程度与年龄、病程无相关性。年龄60岁左右的原发性高血压 患者心率维持在55~ 69 次/min 范围内, 似有利于心肌供血。心功能检测对无症状心功能不全的早期诊断与防治具重要意义。
Abstract:
Investigation of cardiac functional capacity in 234 cases of essential hypertension (EH) campared with 40 normal subjects as controls was performed with a non-invasive synchronous ventricular function detector. The results showed that left ventricular ejection fraction, left ventricular end-diastolic pressure, mean pulmonary capillary wedge pressure, myocardial oxygen consumption, left ventricular end-diastolic volume, left ventricular ejection resistance and modulus of arterial elasticity were higher in patients with EH than in the controls. The myocardial ischemic threshold was lower than in the normal subjects (P<0.01). As mentioned above, the left ventricular diastolic disturbance(LVDD)could be a main early signin EH with asymptomatic heart failure. The severity of LVDD in EH had no significant relation with the course of illness and patients ages. It is suggested that in EH patients around 60 years, the heart rate of 55~ 69 beats/min seems beneficial forprevention of myocardial ischemia. This method is more specific, most sensitive and can be useful for early diagnosis, revention and treatmentin EH with asymptomatic heart failure.

参考文献/References

[1]Betocchi S, Cuocolo A , Pace L , et al. Effects of intravenous verapamil administration on left ventricular diastolic function in systemic hypertension. Am J Cardiol 1987; 59: 624.

[2]王孝铭. 高血压定义. 见: 刘力生, 龚兰生, 孔华宇, 主编. 临床高血压病学. 天津: 科学技术出版社, 1990: 10~ 14.

[3]张子彬, 朱文华, 刘肖林. 左室舒张功能不全性心力衰竭. 见: 张子彬, 郑宗锷, 主编. 充血性心力衰竭. 北京: 科学技术文献出版社, 1991:85~ 87.

[4]全国心衰诊断与治疗专题研讨会纪要. 中华心血管病杂志1995; 23 (2) : 95.

[5]Dougherty AH, N accarelli GV , Gray EL , et al.Congestive heart failure with normal systolic function. Am J Cardiol 1984; 54: 778.

[6]陈德奎. 高血压的脉象研究. 见: 邝安坤, 龚兰生, 主编. 高血压在中国. 湖南: 科学技术出版社, 1989: 68~ 87.

[7]Cohn JN , Johnson G, V eterans Administration Cooperative Study Group. Heart failure with normal ejection fraction. Circulation 1990; 81(Suppl Ⅲ ) : Ⅲ48.

[8]he Criteria Committee of the New York Heart Association. 1994 Revisions to classification of functional capacity and objective assessment of patients with diseases of the heart. Circulation 1994; 90 (1) : 644.

[9]Levine HJ. Optimum heart rate of large failing hearts. Am J Cardiol 1988; 61: 633.

备注/Memo

备注/Memo:
Received 1995-09-25;revised 1996-02-01
更新日期/Last Update: 1996-05-01