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冠心病心率变异性及其诊断价值X(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1997年第4期
页码:
201-204
栏目:
论著
出版日期:
1997-08-01

文章信息/Info

Title:
A study of heart rate variability and its diagnostic value in coronary heart disease
作者:
李上共1　黄元伟1　朱建华1　胡申江1　赵　力2　陈宝仙2　田佩佩2
浙江医科大学附一院　1 心内科　2 心电图室　杭州 310003
Author(s):
Li Shanggong1 ;  Huang Yuanwei1;  Zhu Jianhua1;  Hu Shenjiang1;  Zhao Li2;  Chen Baoxian2; Tian Peipei2
First Affiliated Hospital, Zhejiang Medical University, Hangzhou 310003
关键词:
冠状动脉疾病　心血管造影术　心率变异性　自主神经调节
Keywords:
coronary disease　　angiocardiography　　heart rate variability　　autonomic nervous system function
分类号:
-
DOI:
-
文献标识码:
-
摘要:
本文应用24 h动态心电图对健康人(对照组) 和冠心病心绞痛、心肌梗死患者进行心率变异性研究。结果发现: 心绞痛组和前壁心梗组的正常RR间期总体标准差(SDNN)、每连续5 min时段正常RR间期均值的标准差(SDANN ) 及其平均值(SDNN index)、心率总功率(TP)、极低频功率(VLF)、低频功率(LF) 和高频功率(HF) 等均低于对照组(均P < 0.01) ; 下壁心梗组的SDNN , SDNN index和L F 低于对照组(均P<0.05) ; 前壁心梗组的SDNN,SDANN 和LF低于心绞痛组(均P<0.05)。心率变异诊断冠心病的阳性标准取低于对照组上述任一项指标95% 区间下限值, 则其特异性为93. 9% , 心绞痛组敏感性为51. 2% , 心梗组为71.4%。提示心率变异下降对冠心病的诊断有一定的参考价值。
Abstract:
The time domain and frequency domain of heart rate variability (HRV )were studied in patients with coronary heart disease and normal controls from 24 hour electrocardiography.The results showed that SDNN , SDANN , SDNNindex , TP, VLF, LF and HF were markedly decreased in 41 patients with angina pectoris (Anginas) and 17 patients with acute anterior myocardial infarction (AAMIS) compared with 33 controls (allP< 0.01).SDNN , SDNNindex and LF were reduced in acute inferior myocardial infarction (AIMIS) compared withcontrols(all P<0.05). SDNN , SDANN and LF were reduced in AAMIS compared with Anginas. The abnormality of HRV were diagnosed if the value of any index was lower than the threshold (x-1.96s of controls).The specificity of the diagnosis standard was 93.9%,its sensitivity was 51.2% in Anginas, 71.4% in AMIS. These results indicate that the impairment of autonomic nervous system function are associated with degree of myocardial injury and HRV might be taken as a diagnostic indicator.

参考文献/References

［1］coronary disease angiocardiography heart rate variability autonomic nervous system function.

［2］Akselrod S, Gordon D, Ubel FA , et al. Power spectral analysis of heart rate fluctuation: A quantitative probe of beat-to-beat cardiovascular control. Science, 1981; 213 (4504) : 220.

［3］Kleiger RE, Bigger JT , Bosner MS, et al. Stability over time of variables measuring heart rate variability in normal subjects. Am J Cardiol, 1991; 68 (6) : 626.

［4］Pardo Y,Merz CNB, Paul-Labrador M , et al.Heart rate variability reproducibility and stability using commercially available equipmentin coronary artery disease with daily life myocardial ischemia. Am J Cardiol, 1996; 78 (8) : 866.

［5］Thoren PN.Activation of left ventricular receptors with nonmedullated vagal afferent fibers during occlusion of a coronary artery in cat. Am J Cardiol, 1976; 37 (7) : 1046.

［6］Hayano J , Sakakibara Y, Yamada M , et al. Decreased magnitude of heart rate spectral components in coronary artery disease: Its relation to angiographic severity. Circulation, 1990; 81(4) : 1217.

［7］Ustinova EE, Schultz HD.Activation of cardiac vagal afferents in ischemia and reperfusion:Prostaglandins versus oxygen-derived free radicals. Circ Res, 1994; 74 (5) : 904.

［8］Levy MN , Yang T ,Wallick DW , et al. Assessment of beat-by-beat control of heart rate by the autonomic nervous system: Molecular Biology techniques are necessary, but not sufficient. J Cardiovasc Electrophysiol, 1993; 4 (2) :183.

［9］Ganguly PK,Dhalla KS, Shao,Q,et al.Differential changes in sympathetic activity in left and right ventricles in congestive heart failure after myocardial infarction. Am Heart J,1997;133 (3): 340.

［10］Persson PB, Wagner CD. General principles of chaotic dynamics. Cardiovasc R es, 1996; 31 (3) :332.

［11］Pipilis A , Flather M,Ormerod O , et al. Heart rate variability in acute myocardial infarction and its association with infarct site and clincal course. Am J Cardiol, 1991; 67 (13) : 1137.

［12］Tsuji H, Venditti JFJ , Manders ES, et al. Reduced heart rate variability and mortality risk in an elderly control: Framingham heart study.Circulation, 1994; 90 (2) : 878.

备注/Memo

备注/Memo:
Received 1996-07-18；revised 1997-06-16 X本课题由浙江省教委资助，
更新日期/Last Update: 1997-08-01