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溶栓治疗急性心肌梗死血管再通早晚与心室功能的关系(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1998年第3期
页码:
140-142
栏目:
论著
出版日期:
1998-05-01

文章信息/Info

Title:
Relationship between ventricular function and the time of vessel reperfusion in patients with acute myocardial infarction treated with in travenous thrombolysis
作者:
崔 亮　顼志敏　胡大一　徐 琳　吴亚峰　王 雷
首都医科大学附属北京红十字朝阳医院心脏中心　北京 100020
Author(s):
Cui Liang ;  Xu Zhimin;  Hu Dayi;  Xu Lin;  Wu Yafeng ;  Wang Lei
Heart Center, Beijing Red Cross Chaoyang Hospital, Beijing 100020
关键词:
心肌梗死;  急性　溶栓疗法　心室功能
Keywords:
myocardial infarction;  acute　thrombolytic　ventricular function
分类号:
-
DOI:
-
文献标识码:
-
摘要:
为了探讨溶栓治疗血管再通时间早晚与心脏功能的关系, 对急性心肌梗死(AMI) 患者接受静脉溶栓治疗后, 2周～ 3周行心脏超声测定左室射血分数(LVEF) 及短轴收缩率(FS)。结果: 发病后6 h～ 12 h 期间溶通之患者较6 h 内者其LVEF及FS明显减低, 室壁瘤、Killip Ⅱ级以上者、室壁节段运动消失或反向者出现率则明显增多。提示溶栓治疗应尽早(6 h内) 使AMI梗死相关血管再通。
Abstract:
The purpose of this study is to investigate the relation of cardiac function and vessel reperfusive time in patients with acute myocardial infarction (AMI) receiving intravenous thrombo lytic therapy. The left ventricular ejective fraction (LVEF) and the fractional shortening (FS) were determined by echocardiography 2～ 3 weeks after thrombolysis . The results showed that LVEF and FS were markedly decreased, while the ventricular aneurysm , killip Grade Ⅱ and over, and ven tricular wall segments akinesia were markedly increased in cases of 6～ 12 h group than others. The result demonstrated that the reperfusion of infarct related artery should be finished early (with in 6 h) after AMI onset.

参考文献/References

［1］Cairns JS,Fuster V,Core J,et al.Coronary thrombolysis. Chest, 1995; 108: 401s.

［2］中华心血管病杂志编委会. 急性心肌梗塞溶栓疗法参考方案. 中华心血管病杂志, 1996; 24: 328.

［3］Fibrinolytic Therapy Trialists′(FTT) Collaborative Group. Indications for fibrinolytic therapy insuspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomized trials of more than 1 000 patients. Lancet,1994; 343: 311.

［4］The GUSTO Angiographic Investigators. The effects of tissue plasminogen activator, streptokinase, or both on coronary patency, ventricular function, and survival after acute myocardial infarction. N Engl J Med , 1993;329: 1615.

备注/Memo

备注/Memo:
(收稿1997-09-29)
更新日期/Last Update: 1998-05-01