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|本期目录/Table of Contents|

多巴酚丁胺和潘生丁负荷试验诊断冠心病的临床研究(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1998年第3期
页码:
146-147
栏目:
论著
出版日期:
1998-05-01

文章信息/Info

Title:
Clinical studies of dobutamine and persentin cardiac function tests
作者:
郁晓明1 朱瑞森2 方 杰2 朱继芳2 陆汉魁2 辛丽君2 
上海市第六人民医院 1心脏内科 2核医学科 200233
Author(s):
Yu Xiaoming1 Zhu Luisen2 Fang Jie2 Zhu Jifang2Lu Hankui2 Xin Lijun2
1Department of Cardiology and  2Department of Nuclear Medicine, Shanghai 6th Municipal People′s Hospital, Shanghai 200233
关键词:
冠状动脉疾病 心脏功能试验 多巴酚丁安 潘生丁
Keywords:
coronary disease  heart function tests  dobutamine  persentin
分类号:
-
DOI:
-
文献标识码:
-
摘要:
为了寻找阳性率高的药物负荷试验, 作者对冠心病(CAD) 组和可疑CAD 组共51例患者, 进行多巴酚丁胺(DOB)和潘生丁(PER)负荷试验各1次, 比较DOB 和PER负荷试验的阳性率。结果: DOB与PER负荷试验对血压的影响无显著差异, 但在心率、心律、心电图ST-T 改变及主诉不适等有显著差异。DOB和PER负荷试验的阳性率在CAD 组分别为76.9% 和53.8% , 可疑CAD 组分别为26.3% 和15.8%。DOB试验的阳性率显著优于PER 试验, 更接近运动试验。
Abstract:
Aiming at persuing a higher positive rate in pharmacologic stress imaging, the authors made a comparative study between dobutamine(DOB)and persentine(PER)tests, in which 51 patients with either coronary artery disease (CAD) or suspected CAD were tested and the results were compared. It was found that between the DOB and PER tests, there were signicant differences in heart rate,rhythm ,ST-T segment of electrocardiogram as well as in the patient s′complains, but not in the changes of blood pressure exerted by the tests. The positive rates of DOB and PER in the group of CAD patients were 76.9% and 53.8% respectively; where as those in the group of suspected CAD patients were 26.3% and 15.8% respectively. The positive rate of DOB is hiqher than that of PER and the DOB test works more approximately up to exercise test.

参考文献/References

[1]Verani MS. Dobutamine myocardial perfusion imaging.J Nucl Med , 1994; 35: 737.

[2]Thrall JH. Diagnostic intervention in nuclear medicine.Chicago: Year Book Medical Publishers Inc.1985: 170~ 211.

[3]Iskandrian AS, Heo J , Askense A , et al. Dipyridamole cardial imaging. Am Heart J , 1988; 115: 442.

[4]蒋茂松. 介入性核心脏病学. 见: 刘秀杰, 马寄晓, 主编.临床心肺核医学. 北京: 原子能出版社, 1993: 160~ 165.

备注/Memo

备注/Memo:
(收稿1997-03-25 修回1997-10-07)
更新日期/Last Update: 1998-05-01