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门静脉阻断对家兔左心室功能的影响X(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1998年第4期
页码:
209-210
栏目:
论著
出版日期:
1998-07-01

文章信息/Info

Title:
Effect of portal vein occlusion on cardiac function in left ventricle in rabbits
作者:
王万铁1　林丽娜2　徐正礻介1
1温州医学院病理生理学教研室 温州 325003 2温州医学院附属一院麻醉科
Author(s):
Wang Wantie1;  Lin Lina2;  Xu Zhengjie1
1Department of Pathophysiology, Wenzhou Medical College, Wenzhou 325003　2Department of Anesthesiology, First Affiliated Hospital, Wenzhou Medical College
关键词:
门静脉　心室功能;  左　兔
Keywords:
portal vein　ventricular functiion;  left　Rabbits
分类号:
-
DOI:
-
文献标识码:
-
摘要:
动态观测25只家兔门静脉阻断(PVO) 和再开放(PVR)时左心室功能的变化。实验显示, PVO期间心输出量(CO)、左室内压峰值(LVSP)、左室舒张末期压力(LVEDP) 及左室内压上升、下降最大速率(±dp/dtmax) 均较PVO 前明显下降, 并随阻断时间延长而加重, PVR后部分指标不能恢复至阻断前水平。表明急性门脉阻断对左心室功能有一定的影响。
Abstract:
Changes in the cardiac function in the left ventricle during portal vein occlusion (PVO)and release (PVR) were dynamically observed in 25 rabbits. The exprimental results showed that during PVO the cardiac output(CO) , the left intraventricular summit pressure (LVSP) , the left ventricular end diastolic pressure (LVEDP) and the left ventricular±dp/dtmaxall significantly decreased with the prolongation of the occlusion time, some of which could not be restored to the level of preocclusion after PVR. It is suggested that acute PVO has certain influence on the left ventricular function.

参考文献/References

［1］Gotshall RW , Wood VC, Miles DS. Comparison of two impedence cardiographic techniques for measuring for cardiac output in criticaly ill patients. Crit Care Med , 1989; 17 (8) : 806.

［2］Doi R, Inoue K, Kogire M , et al. Study on splanchinic circulation measurement of the liver blood flow. Nippon Geka Gakkai Zasshi, 1988; 89: 560.

［3］Sahni P, Parde GK, Nundy S. Extrahepatic portal vein obstruction. Br J Surg , 1990; 77 (11) : 1201.

［4］王万铁, 林丽娜, 徐正介.门脉阻断对家兔血液气体的影响.肝胆胰外科杂志, 1995; 7 (2) : 137.

［5］王 卫, 徐正介, 王万铁.门脉阻断及再开放对家兔酸碱平衡的影响1 肝胆胰外科杂志, 1997; 9 (3) : 137.

［6］Swalec KM , Smeak DD, Brown J. Effect of mechanical and pharmacologic manipulations on portal pressure. central venous pressure and heart rate in dogs. Am J Vet Res, 1991; 52 (8) :1327.

[7]Shibayama Y. The relation of endotoxemia to the cause of death and fetal hepatic damage following obstruction of the portal vein. J Pathol, 1990; 160 (4) : 355.

[8]Kunz R, Brune HA , Ziegler U , et al. Ischemia-reperfusion damage of the liver caused by free radicals-direct using electron spin resonance (ESR). Langenbecks Arch Chir, 1991; 376: 139.

［9］akobsson B, El-Hag-IA , Stenram U. Nucleotide profile in rat liver and intestine at portal vein obstruction and flow. Biomed Biochim Acta, 1991; 50 (8) : 1001.

备注/Memo

备注/Memo:
(收稿1997-10-26　修回1998-05-18)X浙江省卫生厅科研基金资助课题
更新日期/Last Update: 1998-07-01