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《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:

1999年第3期

页码:

157-158,168

栏目:

论著

出版日期:

1999-05-01

文章信息/Info

Title:

A clinical study in assessment of myocardial fibrosis with ultrasonic backscatter parameters

作者:

朱永胜　钱蕴秋　周晓东　张　军　李　军　陈宇翔

第四军医大学西京医院超声诊断科 西安 710032

Author(s):

Zhu Yongsheng ;  Qian Yunqiu ;  Zhou Xiaodong ;  Zhang Jun;  Li Jun;  Chen Yuxiang

Department of Ultrasound, Xijing Hospital, Fourth Millitary University,Xi′an 710032

关键词:

超声背向散射　心肌纤维化　组织定征

Keywords:

ultrasonic backscatter 　myocardial fibrosis　tissue characterization

分类号:

-

DOI:

-

文献标识码:

-

摘要:

为评价超声背向散射参数判定心肌组织纤维化的临床价值。采用HP SONOS 2500 型超声检查仪观测24例陈旧性心肌梗死(OMI)患者梗死灶、38例扩张型心肌病(DCM)和45例Ⅱ型糖尿病(DM)患者、正常对照组40例室间隔、左室后壁心肌的背向散射参数——背向散射积分(IBS)和IBS的心动周期变化幅度(CVIB)。结果:OMI梗死灶、DCM 和Ⅱ型DM患者心肌的校正IBS (IB%)平均值均显著增大, CVIB均降低或出现IBS曲线形态明显异常。IB%、CVIB对OM I、DCM、DM均有较高的阳性预告值和阴性预告值。结论: 背向散射参数对判定心肌病变、判断心肌纤维化程度较为客观、简便, 有较高的临床应用价值。

Abstract:

We sought to assess the value of ultrasonic backscatter parameters in the determination of myocardial fibrosis. Myocardial ultrasonic backscatter parameters of patients with old myocardial infarction (OMI, 24 cases),dilated cardiomyopathy(DCM,38 cases),diabetes mellitus (DM , 45 cases) and 40 members of normal control group were measured by a commercially available modified real-time backscatter signal 2D imaging system(HP SONOS 2500).Results: Time-averaged values of corrected myocardial IBS(IB%) of previously infarcted myocardium foci and IVS or LVPW of patients with DCM or DM were all significantly greater than those of the normal. For most patients, patterns of time-IBS curve turned out to be abnormal and CVIB values decreased greatly. IB% , CVIB brought about high positive or negative predictive values to OMI, DCM and DM. Conclusion: Ultrasonic backscatter was useful in determining myocardial abnormality and assessing the degree of myocardial fibrosis. It is an objective and direct technique for clinical application.

参考文献/References

［1］朱 霆, 钱蕴秋. 超声背向散射积分与心肌组织定征. 国外医学生物医学工程分册1997; 20 (2) : 102.

［2］武忠弼. 病理学. 第4 版. 北京: 人民卫生出版社, 1996: 197～204.

［3］Perez JE, McGill JB, Santiago JV , et al. Abnormal myocardial acoustic properties in diabetic patients and their correlation with the severity of disease. J Am Coll Cardiol, 1992; 19 (6) : 1154.

［4］Vered Z, Mohr GA , Baezilai B, et al: Ultrasonic backscatter tissue characterization of remote myocardial infarction in subjects. J Am Coll Cardiol, 1989: 13 (1) : 84.

［5］Vered Z, Baezilai B, Mohr GA , et al: Quantitative ultrasonic tissue characterization with real-time backscatter imaging in normal human subjects and in patients with dilated cardiomyopathy. Circulation, 1987: 76 (5) : 1067.

［6］ Masuyama T,Stgoar F,Tye TL,et al.Ultrasonic tissue characterization of human hypertrophied heart in vivo with cardiac-depended variation in integrated backscatter.Circulation.1989;80 (7):925.

［7］ 赵柯湘,肖谦, 黄昶荃,等. 糜蛋白酶活性与链脲菌素诱导糖尿病仓鼠心肌病变的研究［J］. 中华老年心脑血管病杂志, 2007, 9(1):49-52Natio J , Masuyama T, Mano T, et al. Ultrasonic backscatter tissue characterization in patients with dilated cardiomyopathy:Value in noninvasive assessment of myocardial fibrosis. Am Heart J , 1996; 131 (1) : 115.

备注/Memo

备注/Memo:

(收稿1998-10-15　修回1999-01-11)

常用功能

更新日期/Last Update: 1999-05-01