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|本期目录/Table of Contents|

甲状腺激素治疗充血性心力衰竭的研究进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1999年第3期
页码:
188-190
栏目:
综述
出版日期:
1999-05-01

文章信息/Info

Title:
-
作者:
马建林 陈 萍 综述 苏哲坦 审校
海南省人民医院心内科 海口 570311
Author(s):
-
关键词:
心力衰竭 充血性 甲状腺激素
Keywords:
-
分类号:
-
DOI:
-
文献标识码:
-
摘要:
近年来国内外研究发现, 充血性心力衰竭(CHF)患者体内存在着甲状腺激素代谢异常,表现为T3水平降低,T4水平降低或正常,rT3水平升高以及TSH水平正常。其严重程度与心衰的严重程度密切相关,其病理过程主要包括甲状腺激素对心脏和血管的效应以及调节对儿茶酚胺的反应性两个方面, 其代谢异常可以导致CHF患者的心脏和血管功能进一步异常。初步研究表明, 在常规心衰治疗基础上给予短疗程小剂量甲状腺激素治疗将利于纠正顽固性心衰,缩短疗程。其机制可能与纠正了CHF患者体内的低甲状腺激素水平状态, 使得甲状腺激素正常生理功能得以发挥有关。
Abstract:
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参考文献/References

[1]Hamilton MA.Prevalence and clinical implications of abnormal thyroid hormone metabolism in advanced heart failure.Ann Thorac Surg,1993;56:S48.

[2]Klein I,Ojamaa K.Thyroid hormone treatment of congestive heart failure.Am J Cardiol,1998;81(4): 490.

[3] Utiger RD.Altered thyro d function in nonthyroidal illness and surgery:to treat or not to treat.N Engl J Med,1995;333:1562.

[4] Polikar R,Rurger AG,Scherer U,et al.The thyroid and the heart.Circulation,1993;87:1435.

[5] Ojamma K,Samarel A,Kupfer J,et al.Thyroid hormone effects on cardiac gene expression independent of cardiac growth and protein synthesis.Am J Physiol,1992;263:E534.

[6] Klemperper JD,Zelano J,Helm R,et al.Triiodothyronine improves left ventricular function without oxygen wasting effects following global hypothermic ischemia.J Thorac Cardiovasc Surg,1995;109:457.

[7] Martin WH,Spina RJ,Korte E.Effect of hyperthyroidism of short duration on cardiac sensitivity of β-adrenergic stimulation.J Am Coll Cardiol,1992;19:1185.

[8] Ririe DG,Butterworth JF, Royster RL,et al.Triiodothyronine increases contractlity independent of β-adrenergic receptors of stimulation of cyclic 3′, 5′-adenosine monophosphate.Aesthesiology .1995;82(4):1004.

[9] Epstein FH,Brent GA.The molecular basis of thyroid hormone action.N Engl J Med,1994;331:847.

[10]Slater A.Thyroid diseases and heart.Practial Cardiol,1991;17:28.

[11]Moruzzi P,Doria E,Agostini PG,et al.Usefulness of I-thyroxine to improve cardiac and exercise performance in idiopathic dilated cardiomyopathy.Am J Cardiol,1994;73:374.

[12]Hamilton MA,Stevenson LW,Fonarow GC,et al.Safty and hemodynamic effects of intravenous triiodothyronine in advanced congestive heart failure.Am J Cardiol,1998;81(4):443.

[13]Klemperer JD,Klein I,Gomez M,et al.Effects of thyroid hormone supplementation in cardiac surgery.N Engl J Med,1995;333:1622.

[14]Klemperer JD,Ojamaa K,Klein I.Thyroid hormone therapy in cardiovascular disease1.Prog Card iovasc Dis,1996;38:329.

备注/Memo

备注/Memo:
(收稿1998-09-30 修回1999-02-10)
更新日期/Last Update: 1999-05-01