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|本期目录/Table of Contents|

对声学定量技术测定小儿扩张型心肌病患者左室功能的评价(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2000年第2期
页码:
90-92
栏目:
论著
出版日期:
2000-03-25

文章信息/Info

Title:
Evaluation of acoustic quantification to assess left ventricular function in children suffered from dilated cardiomyopathy
作者:
王现;  林其珊;  陈伟达
上海医科大学附属儿科医院, 上海 200032
Author(s):
WANG Xian; LIN Qi-shan; CHEN Wei-da
Pdeiatric Hospital,Shanghai Medical University,Shanghai 200032
关键词:
声学定量技术; 左室功能; 心肌病; 充血型
Keywords:
Acoustic Quantification; two-dimensional echocardiography; left ventricular function; cardiomyopathy; congestive
分类号:
R540.45
DOI:
-
文献标识码:
A
摘要:
目的 探讨声学定量(AQ)技术检测小儿扩张型心肌病患者的左室功能的应用价值并评价患儿的心功能改变。方法 应用声学定量技术、二维越声心动图(2-DE)及多普勒越声心动图(PDE)检测16例扩张型心肌病(DCM)患儿的左室功能,并对两种方法进行对比研究,探讨二者间的一致性。结果 本组患儿93%可进行AQ技术检查;后者可取代2-DE测定小儿DCM的左室面积指标、射血分数,但两者测定的左室容积指标一致性尚欠佳;DCM患儿的左室舒张末期及收缩末期面积增大,面积变化分数、射血分数降低,显示左室收缩功能受损;对扩张型心肌病患儿左室舒张功能检测表明,AQ技术敏感性高于PDE,尤其PDE二尖瓣血流频普显示假性正常时。AQ技术与PDE的联合应用,更有利于小儿左室舒张功能的检测。结论 AQ技术可实时、快速、可靠地进行小儿DCM心功能检测,为临床药物的选择、疗效和预后的判断提供依据。
Abstract:
Object This study was to set up normal values of Acoustic Quantification(AQ) in children who suffered from dilated cardiomyopathy(DCM) and to compare the AQ with two-dimensional echocardiography. Method The left ventricular function of 16 children of DCM was studied by two-dimensinal echocardiography (2-DE) and AQ. The measurements of left function were compared between the two methods. Result 93% patients of DCM had a technically adequate conventioinal echocardiograpy. End-diastolic area,end-systolic area,area change fraction and ejection fraction which were measured by these two methods were consistent,but the measurement of left ventricular diastolic end volume and systolic end volume of AQ were under-estimated comparing with that of 2-DE. Criteria for abnormal relaxation were present in 80% by AQ and in 20% by Doppler echocardiography(PDE). Abnormal relaxation was detected by AQ while normal presence in PDE. Conclusion The AQ provides a new,clinical useful method for real-time estimation of the left ventricular function. But it is associated with cavity volume measurement errors that need to be addressed.

参考文献/References

［1］ Shah PM,Crawford M,DeMaria A,et al. Recommedationl for quantitation of the left ventricle by two-dimensional echocardiography［J］. J Am Soc Echo,1989,2:258.

［2］ Perez JE,Waggoner AD,Barzilai B,et al. On-line Assessment of ventricular function by automatic boundary detection and ultrasonic backscatter imaging［J］. J Am Coll Cardiol,1992,19:313.

［3］ Vered Z,Barzilai B,Mohr GA,et al. Quantitative ultrasonic tissue characterization with real-time integrated backscatter imaging in normal human subjects and patients with dilated cardiomyopathy［J］. Circulation,1987,76:1067.

［4］ Foster E,Michael FK,Cahalan MD. The search for intelligent quantitation in echocardiography: “Eyeball”,“Trackball” and beyond［J］. J Am Coll Cardiol,1993,22:848.

［5］ Bland JM,Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement［J］. Lancet,1986,1:307.

［6］ Julio E,Perez MD,Steve C,et al. Automated,on-line quantification of left ventricular dimensions and function by echocardiography with backscatter imaging and lateral gain compensation［J］. Am J Cardiol,1992,70:1200.

备注/Memo

备注/Memo:
收稿日期：1998-12-04.
更新日期/Last Update: 2000-03-25