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|本期目录/Table of Contents|

心率变异性与高血压病程和血管紧张素Ⅱ浓度的相关性(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2000年第6期
页码:
443-445
栏目:
论著
出版日期:
2000-12-01

文章信息/Info

Title:
The correlation between the course of hypertension and the plasma level of angiotension Ⅱ with heart rate variability
作者:
乔怀宇;  赵连友;  徐海丽;  杨学东;  彭育红
第四军医大学唐都医院心血管内科, 陕西西安710038
Author(s):
QIAO Huai-yu; ZHAO Lian-you; XU Hai-li; YANG Xue-dong; PENG Yu-hong
Department of Cardiology, Tangdu Hospital, Fourth Military Medical University, Xi'an Shaanxi 710038, China
关键词:
高血压;  血管紧张素II ;  心率变异性
Keywords:
hypertension;  angiotensin Ⅱ;  heart rate variability
分类号:
R544.1;R544.41
DOI:
-
文献标识码:
A
摘要:
目的 观察高血压病患者血浆血管紧张素 (AT)、高血压病程对心率变异性 (HRV)的影响。方法 采用2 4h动态心电图分析系统测量 HRV指标 ,血浆 AT 的浓度采用放射免疫法测定 ,检测结果进行多重相关分析。结果 HF,L F,SDANN,PNN5 0 等指标随高血压病程延长均降低 ,两者呈负相关 (相关系数分别为:r=- 0 .5 9,P<0 .0 5 ;r=- 0 .5 7,P<0 .0 5;r=- 0 .5 9,P<0 .0 5 ;r=- 0 .38,P>0 .0 5 ) ,除与 PNN5 0 外 ,其余有统计学意义。高血压病患者 HF,L F,SDANN,PNN5 0 随血浆 AT 的浓度升高均升高 ,两者呈正相关 (相关系数分别为:r=0 .79,P<0 .0 1;r=0 .91,P<0 .0 1;r=0 .77,P<0 .0 1;r=0 .79,P<0 .0 1) ,均有明显的统计学意义。结论 高血压患者HRV与血浆 AT 的关系较其与病程的关系更为密切 ,血浆 AT 浓度与 HRV各指标的变化相平行。
Abstract:
AIM To investigate the correlation of the plasma level of angiotensin Ⅱ(ATⅡ) and the course of hypertension with heart rate variability(HRV). METHODS Immunoradiometric assay was used to measure the plasma level of ATⅡ, Holter was used to analysis HRV, the results were tested by multiple correlation analysis. RESULTS As the course of hypertension prolonged, HF,LF,SDANN,PNN 50 decreased, there were negative correlation between them. The correlation coefficient were r =-0. 59, P <0.05; r=-0. 57, P<0. 05; r=-0.59, P<0.05; r=-0.38, p>0.05 respectively. As the concentration of the plasma AT II increased, HF, LF, SDANN, PNN50 increased, there were positive correlation between them. The correlation coefficient were r=0.79, P<0.01; r=0.91, P<0.01; r=0.77, P<0.01; r=0.79, P<0.01 respect ively. CONCLUSION The plasma level of AT II has a closer correlation with HRV than the course of hypertension with it, the change of the concentration of the plasma AT II parallel the change of HRV.

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备注/Memo

备注/Memo:
收稿日期：1999-11-10.
更新日期/Last Update: 2000-12-01