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|本期目录/Table of Contents|

血浆心房钠尿肽水平、右心压力及心功能分级的相关性(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2000年第6期
页码:
469-470
栏目:
论著
出版日期:
2000-12-01

文章信息/Info

Title:
Relationship between plasma atrial natriuretic peptide concentration,right heart pressures and cardiac functional class
作者:
赵永进;  刘晋黎;  胡端忍;  张碎虎;  石勤生;  王秀芝;  崔如明
酒泉钢铁公司医院心血管内科, 甘肃嘉峪关735100
Author(s):
ZHAO Yong-jin;  LIU Jin-li;  HU Duan-ren;  ZHANG Sui-hu;  SHI Qin-sheng;  WANG Xiu-zhi;  CUI Ru-ming
Jiu Gang Hospital, Jiayuguan Gansu 735100, China;
关键词:
心钠素;  心力衰竭;  充血性;  Swan-Ganz导管术
Keywords:
atrial natriuretic factor;  heart failure;  congestive;  Swan Ganz cathet
分类号:
R541.6
DOI:
-
文献标识码:
A
摘要:
目的 观察血浆心房钠尿肽 (ANP)浓度、各部位压力及心功能分级之间的关系。方法 对 2 0例充血性心力衰竭(CHF)患者通过漂浮导管 (Swan- Ganz导管 )同时测定肺动脉、右心室、右心房的压力 ,并用放射免疫法测定上述三个部位血浆心房钠尿肽 (ANP)浓度。结果 CHF患者心功能级别不同 ,心血管各部位的压力及血浆 ANP浓度也不同 ;心血管内各部位的压力和血浆 ANP浓度与心功能不全的严重程度相平行 ;股静脉及肺动脉血浆 ANP浓度均与上述三个部位压力呈正相关 ;在心功能分级相同时 ,各部位血浆 ANP浓度基本相同。结论 有可能通过测定外周血浆心房钠尿肽浓度判断心功能不全程度 ,或估计肺动脉、右心房、股静脉处的压力。
Abstract:
AIM To investigate the relationship between atrial natriuretic peptide(ANP) concentration,pressure and cardiac functional class. METHODS Plasma ANP concentrations and pressures in the pulmonary artery(PA),the right ventricle(RV) and the right atrium (RA) were measured by Swan Ganz catheter and radioimmunoprecipitation respectively in twenty different cardiac functional class patients with congestive heart failure (CHF). RESULTS The results showed that the pressures of the three different positions,plasma ANP concentrations and the severity of CHF had a correlation with one another. The plasma ANP concentrations were similar in the cases in the same cardiac functional class. CONCLUSION These data suggest that the pressures of PA , RA and RV, and the severity of CHF may be assessed by peripheral venous ANP concentrations.

参考文献/References

[1] Drexler H, Fillkh M, Hoing S, et al. Systemic and regional vascular effects of atrial natriuretic peptide in a rat model of chronic heart failure[J]. Basic Res Cardiol, 1987, 82 (6) : 517.

[2] Amin DA, Shah PK. Swan-Ganz catheter: Insertion technique [J]. Jcritillness, 1986, 1 (4) : 38.

[3] 陈泮藻, 李振甲, 郝秀华, 等. 心钠素快速放射免疫分析[J]. 中华核医学杂志, 1986, 6 (3) : 147.

[4] Daridson MB, Barr MB, Struthers MD. C-type natriuretic peptide - an endogeous inhibitor of vascular angiotensin converting enzyme activity[J]. Circulation, 1996, 93 (6) : 1155.

[5] 许项立, 翁昌鸿, 任　吴, 等. 经皮二尖瓣成形术患者血浆心钠素和血管加压素水平的改变[J]. 中国循环杂志, 1994, 9 (12) :727.

[6] Nakamura M, Arakawa N, Abe Y, et al. Relationship between plasma atrial natriuretic peptide concentration and atrial pressure in acute and chronic heart failure [J]. Jpn Heart J ,1990, 31 (4) : 425.

备注/Memo

备注/Memo:
收稿日期：1999-12-30.
更新日期/Last Update: 2000-12-01