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|本期目录/Table of Contents|

冠心病患者血清抗心磷脂抗体变化与血脂的关系(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2001年第1期
页码:
50-51,53
栏目:
论著
出版日期:
2001-01-25

文章信息/Info

Title:
The relationship of change of anticardiolipin antibody and blood lipid in patients with coronary heart disease
作者:
刘松岩韩凤英宋 萱扬欣国
第四军医大学唐都医院心内科,陕西西安71O032
Author(s):
LIU Song-yanHAN Feng-yingSONG XuanYANG xi-guo
Department of Cardiology,Tangdu Hospital,Fourth Military Medical University,Xi an Shaanxi 710038,China
关键词:
冠状动脉疾病抗心磷脂抗体血脂
Keywords:
coronary diseaseanticardiolipin antibodyblood lipid
分类号:
R514.4
DOI:
-
文献标识码:
A
摘要:
目的 探讨抗心磷脂抗体(ACA)在冠心病(CHD)发病中的意义及其与血脂的关系。方法 52例CHD患者及44名健康体检者分别用ELISA和免疫避射比浊法测定血清ACA-IgG,ACA-IgM,ACA-IgA和TC,TG,HDL,ApoA-I,ApoB的含量.结果 冠心病组的ACA-IgG水平明显高于正常对照(P<0.O1),而ACA-IgG变化的水平与TG,HDL,ApoA-I改变星显著的相关关系(r分别为0.31,-0.27和-0.29,均P<0.01).结论 血清ACA-IaG可与血脂代谢紊乱可能共同形成CHD的发病机制或有促进血脂代谢紊乱的作用。
Abstract:
AIM To study the role of anticardiolipin antibody (ACA )in coronary heart disease (CHD)and the relationship of blood lipid in CHD patients.METHODS Serum ACA-IgG,IgM ,lgA and TC,TG,HDL,ApoA-I,ApoB were measured by ELISA and immune turbidity assay in 52 CHD patients and in 44 healthy people.RESULTS The levels of ACA-lgG of the CHD group were markely higher than those of the control group(P< 0.01)and changes in ACA—IgG levels of were closely associated with TG ,HDL,ApoA-I(r= 0.31,P< 0.01,99% CI 0.05~ 0.53;r=-0.27,P< 0.01,99% CI -0.01~-0.49;r=-0.29,P< 0.Ol,99% CI -0.03~ -0,51).CONCLUSION The high level serum ACA-lgG autoantibody may play a role mediated pathogenesis of CHD.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期:2000-04-26.
更新日期/Last Update: 2001-01-25