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《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:

2001年第2期

页码:

84-86

栏目:

论著

出版日期:

2001-03-01

文章信息/Info

Title:

Influence of balloon predilation pressure before stent implantation in de novo coronary artery lesion on clinical outcome

作者:

贾国良．曹丰; 李成祥; 郭文恬．李伟点; 王小燕

第四军医大学西京医院心脏内科，陕西西安710032

Author(s):

JIA Guo-liang; CAO Feng; LI Cheng-xiang; GUO Wen-yi; LI Wei-jie; WANG Xiao-yan

Department of Cardiology，Xijing Hospital，Fourth Military Medical University，Xi'an Shaanxi 710032，China

关键词:

冠状动脉疾病; 血管成行术; 经腔; 经皮冠状动脉; 预扩张; 压力; 支架

Keywords:

coronary disease; angioplasty; translumlnal; percutaneous coronary; pressure; predilation; stent

分类号:

R541.4

DOI:

-

文献标识码:

A

摘要:

目的 评估球囊低压力预扩张对冠脉内支架术后临床疗效的影响。方法 依据不同球囊预扩张压力将入选的91例冠心病患者分为低压力组(最大扩张压力≤12 atm)、高压力组(>12 atm)．观察住院期间严重临床事件率和术后6～18个月无心脏事件存活率。结果 低压力组球囊最大预扩张压力为8．3±1．6 atm，高压力组为13．9±0.3arm (P<0.05)，144个支架均成功置入。低压力组和高压力组在术中的血管夹层及撕裂的发生率分别为8．2% 和19．0% (P<0．05)．住院期间低压力组发生死亡为0例，高压力组为1例；68例患者接受了术后6～18个月的临床随访．无心脏事件存活率低压力组为74%，高压力组为61%，其中13例在随机冠状动脉造影随访中发现支架内再狭窄．低压力组为6例，高压力组为7例。结论 低压力球囊预扩张可减少支架术中的急性血管并发症，不影响支架置入的远期疗效。

Abstract:

AIM To assess the role of low-pressure pre-dilation in the clinical outcome of patients undergoing percutaneous transluminal coronary angioplasty(PTCA)and stenting． METHODS Ninety-one patients with coronary heart disease treated with PTCA and stenting were assigned into low-(≤ 12 atm ，49 patients)or high-(> 12 atm ，42 patients)balloon-pressure pre-dilation．The event-free survival at 6～18 months follow-up and the incidence of adverse clinlca1 events during the hospitalization were investigated．RESULTS The maximal balloon pre-dilation pressure was 8．3士1．6 atm in low-pressure group，and 13．9士0.3 arm in high-pressure group(P<0.05)． During the hospitalization，there was no Q-wave myocardial infarction in low-pressure group，but one in high-pressure group who underwent repeat PTCA． The incidence of adverse vessel events during the operation was 8．2% for low-presure pre-dilation and 19．0% for high-pressure group(P< 0．05)．Event-free survival at 6～18 months follow-up was not significantly different between the two groups．CONCLUSION The use of low-pressure balloon pre-inflation before coronary stent placement reduces the incidence of acute vascular complication while is not associate with any significant influence on the 6～18 months outcome of patients undergoing this intervention．

参考文献/References

[1]Savage MP，Fischman DL,Rake R，et al.Efficacy of coronary stenting versus balloon anginplasty in small coronary arteries. Stent Restensis Study(STRESS)Investigators[J]．J Am Coll Cardio1．1998,31(2):307．

[2]Roubm GS．Cannon AD，Agrswal SK．et al．Intracoronary stenting for acute and threatened closure complicating percutaneous transluminal coronary anginplasty[J].Circulation，1992，95：9l9．

[3] Wilents JR，Sanborn TA．Haudensehild CC，et al．Platelet accumulation in experimental anginplasty：time course and relation to vascular iniury[J]．Circulation，1987，75(3)：636．

备注/Memo

备注/Memo:

收稿日期：2000-05-17.

常用功能

更新日期/Last Update: 2001-03-01