我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

冠心病C反应蛋白及甘油三酯／高密度脂蛋白胆固醇比值变化的研究(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2001年第2期
页码:
130-132
栏目:
论著
出版日期:
2001-03-01

文章信息/Info

Title:
The changes of the levels of C-Reactive protein and TG／HDL-C ratio in patients with coronary heart disease
作者:
赵季虹; 张利华; 薛玉生; 周秀荣; 那桂平
第四军医大学唐都医院心内科，陕西西安710038
Author(s):
ZHAO Ji-hong; ZHANG Li-hua; XUE Yu-sheng; ZHOU Xiu-rong; NA Gui-ping
Department of Cardiology，Tangdu Hospital，Fourth Military Medical University．Xi'an Shaanxi 710038．China
关键词:
冠状动脉疾病; C反应蛋白; 脂蛋白类; 甘油三酯
Keywords:
coronary disease; C-Reactive protein; lipoproteins; triglyceride
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 探讨冠心病(CHD)病情程度与C反应蛋白(CRP)及甘油三酯／高密度脂蛋白胆固醇(TG/HDL-C)比值的关系．方法 测定128倒CHD患者的血浆CRP浓度、TG浓度、HDL-C浓度及TG／HDL-C 比值，并与对照组(健康者120例)相比较，分析CRP及TG／HDL-C比值的临床意义。结果 CRP浓度及TG／HDL-C比值在对照组、稳定型心绞痛组、不稳定型心绞痛组分别为：2293±108ug／L，1．87±0．41；5216±328ug／L，3．26±0．81；13811±861ug／L，3.66±1.02；稳定型心绞痛组及不稳定型心绞痛组明显高于对照组(分别为P<0．05、P<0．01)。CHD组中，两指标在慢性充血性心力衰竭I。组、II。组、III。组中分别为：5981±391ug／L，2．02±0．39；11912±908ug／L，3．61±0．99；13213±989ug／L，4．82±1．09；心力衰竭II。组、III。组明显高于心力衰竭I。组(P
Abstract:
AIM To study the relation of the plasma C-Reactive protein (CRP)and triglyceride／high density 1ipoprotein-cholestero1(TG／HDL-C)ratio to the severity of coronary heart disease (CHD)． METHODS The plasma CRP concentration，TG concentration．HDIL-C concentration and TG／HDL-C ratio were tested in 128 patients，and were compared with those of the normal contro1 group(n=120)，in order to analyse the clinica1 significance of CRP and TG／HDL-C ratio．RESULTS The plasma CRP concentration and TG／HDL-C ratio were，3293士108 ug／L and 1.87士0．4l，52l6士328 ug／L and 3．26士0．81，1381l士861 ug／L and 3．66士1．02，respectively,for the normal contro1 group，the stable angina group，and the unstable angina group．The two indices in the stable and the unstable angina groups were significantly higher than those of the normal control group (respectively P<0．05，P<0．O1)．and were, 5981士391 ug／L and 2．02士O．39，l1912士908 ug／L and 3.61士0．99，13213士989 ug／L and 4．82士1．09，respectively，for the chronic congestive heart failure (CHF)I。,II。and III。groups．The two indices in CHF Il。group and III。groups were significantly higher than those of CHF I。group(P<0．01)．The plasma CRP concentration and TG concentration were positively correlated (r= 0．54，P< 0．05)．The plasma CRP concentration and HDL-C concentration were negatively correlated (r=-0．15．P< 0．01)．CONCLUSION CRP and TG／HDL-C ratio serve predicting indices for clinical evaluation of severity and prognosis in CHD、CRP and 1ipoprotein were correlated．

参考文献/References

[1]Fabricant CG，Fabricant J，Litrenta MM,et a1．Virus-induced atherosclerosis[J]．J EXP Med，1978,148：335．

[2]Mehta JI，Saldeen TG, Rand K．Interactive role of infection,inflammation and traditional risk factors in atherosclerosis and coronary artery disease[J]．J Am Coll Cardiol.1998,31:1217．

[3]王彬尧,王长谦，郑道声．甘油三酯与冠心病的关系[J]．国外医学心血管疾病分册，2000，27(2)：79．

[4]Anderson JL．Evaluation of C-Reactive protein，an inflammatory marker,and infectious serology as risk factors for corotrary disease and myocardial infarction[J].J Am Coll Cardiol，1998，32:35．

[5]Tataru MC,Heinrich J，Junker R,et al．C-Reactive protein and the severity of atherosclerosia in myocardial infarction patients with stable angina pectoris[J]．Eur Heart J．2000,21：1000．

[6]孙宁玲，李明.慢性充血性心力衰竭患者血浆中C-反应蛋白、肾上腺髓质素及内皮素水平变化的研究[J]．中国循环杂志，2000，15(1)：37．

[7]Larosa JC. Triglycerides and coronary risk in women and the elderly[J]．Arch Intern Med，1997,156:461．

[8]Syvanne M．Lipid and lipoproteins as coronary risk factors in NIDDM diabets and the heart disease [J]．Lancet.1997，350(SupplI):1．

[9]张明, 霍海洋，李占全，等．甘油三酯／高密度脂蛋白胆固醇比值对冠心病的诊断价值的探讨[J].中华心血管病杂志，2000，28(1)：33．

[10]Laurila A，Bloigu A，Nayha S，et al.Chronic Chlamydis pneumoniae infection is associated wiht a serum lipid profile known to be a risk factor for atherosclerosis[J]，Arterioscler Thromb Vasc Biol，1997，17:2910．

备注/Memo

备注/Memo:
收稿日期：2000-07-05.
更新日期/Last Update: 2001-03-01