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多巴酚丁胺负荷试验中多普勒组织成象评价冠心病左室整体舒张功能(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2001年第4期
页码:
271-273
栏目:
论著
出版日期:
2001-07-01

文章信息/Info

Title:
Application of Doppler tissue imaging to a ssessment of global diastolic function of left ventricle in coronary artery disease during dubitamine stress
作者:
李 楠1 钱蕴秋1 张 军1 周晓东1 朱永胜1 吴巧英1 李 寰2
第四军医大学西京医院:1.超声诊断科,2 心脏内科,陕西西安710032
Author(s):
LI Nan1QIAN Yun-qiu1 ZHANG Jun1 ZHOU Xiao-dong1 ZHU Yong-sheng1WU Qiao-ying1LI Huan2
1. Ultrasound Divison, Xijing Hospital, Fourth Military Medical University, Xi’an Shaanxi 710032, China
关键词:
冠状动脉疾病 多普勒组织成像 多巴酚丁胺负荷试验 超声心动描记术 左室整体舒张功能
Keywords:
coronary disease Doppler tissue imaging dubitamine stress echocardiography global diastolic function left ventricle
分类号:
R540.45
DOI:
-
文献标识码:
A
摘要:
目的 探讨多巴酚丁胺(DBA) 负荷中多普勒组织成象(DTI) 检测冠心病患者左室整体舒张功能的变化。方法 冠心病患者30 例, 正常人18 例, 按5min 递增法以5, 10, 15, 20, 30 Lg.kg- 1.min- 1浓度静注DBA ,DTI 记录注药前及每一剂量级时二尖瓣环运动情况。结果 正常组注药后Ea 增加明显, 但Ea/Aa 略有下降, 无显著差异。单支病变组Ea 升高不显著。Ea/Aa 则明显减低。多支病变组Ea, Ea/Aa 均显著减低。单支病变组、多支病变组Ea/Aa 注药前、后均低于正常组, 差异显著。且注药前、后二尖瓣平均舒张速度变化率△Ea% 及△Ea、Aa% 显著低于正常组。结论 DTI 测量二尖瓣环舒张期运动速度可用于负荷试验中评价左室整体舒张功能。
Abstract:
AIM To evaluate the application of Doppler tissue imaging (DTI) with dubitamine (DBA) stress echocardiography to assessment of global diastolic function of left ventricle for detection of coronary artery disease (CAD). METHODS 30 patients with CAD and 18 subjects of normal control group underwent dubitamine stress echocardiography, and they were given addied doses of 5, 10, 15, 20, 30 Lg.kg-1.min-1 per 5 minutes, and their velocities of mitral valve annular were measured by DTI.RESULTS Ea increased significantly and Ea/Aa decreased a little but not significantly in the control group after dubitamine injection. Ea increased in significantly and Ea/Aa decreased significantly in the group with single coronary artery branch stenosis. Both Ea and Ea/Aa decreased significantly in the group with more than one coronary artery branches stenosis. Ea, Ea/A a, △Ea% and △Ea/Aa% in the two CAD groups were all significantly lower than those of the control group either before or after the medication. CONCLUSION Velocities of mitral valve annular were measured by DTI and can be used to assess global diastolic function of the left ventricle during dubitamine stress test.

参考文献/References

[1] Greenbaum RA , Ho LY, Gibosn GD, et al. Left ventricular fibre architecture in man [J]. Br Heart J , 1981, 43(3): 248-263.

[2] Alam M , Thorstrand C. Left ventricular function in patients with atrial fibrillation before and after cardioversion [J]. Am J Cardiol, 1992, 69(8): 694-696.

[3] 诰朝晖, 杨浣宜, 汤五洲. 用超声心动图房室平面位移法评估冠心病左室功能[J]. 中国超声医学杂志, 1999, 15(11): 840-843.

[4] Miyatake K, Yamagishi M , Tanaka N , et al. New method for evaluating in vitro and in vivo studies[J], JACC, 1995, 25(3):717.

[5] Farias CA , Rodriguez L , Sun JP, et al. Assessment of diastolic[J]. Circulation, 1997, 96(Suppl I): 343.

[6] Sohn DW , Chai IH,Lee DJ , et al. Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function [J]. JACC, 1997, 30(2): 474-480.

备注/Memo

备注/Memo:
收稿日期:2000-05-22.
更新日期/Last Update: 2001-07-01