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|本期目录/Table of Contents|

转基因预防冠状动脉再狭窄(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2002年第4期
页码:
345-347
栏目:
讲座与综述
出版日期:
2002-07-01

文章信息/Info

Title:
-
作者:
赵智深 综述; 黄从新 审校
湖北医科大学一附院心内科,湖北武汉430060
Author(s):
-
关键词:
术后再狭窄; 冠状动脉; 血管成形术; 经腔; 经皮冠状动脉; 基因
Keywords:
-
分类号:
R541.4;R540.46
DOI:
-
文献标识码:
A
摘要:
作者复习了近年基因治疗冠状动脉成形术后再狭窄的动物实验研究进展,对细胞休眠法、细胞毒法和旁分泌法等3种主要基因治疗方法进行综述。
Abstract:
-

参考文献/References

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[2] Goerge SJ,Johnson JL,Angelini GD,et al. Expression of tissue inhibitor of metallo-proteinase-1,-2 and -3 during neointimal formation in organ culture of human saphenous vein[J].Hum Gene Ther,1998,9:867.

[3] Dolery CM,Humphries SE,Mc Celland A,et al. Expression of tissue inhibitor of matrix metalloproteinases 1 by use of an adenoviral vector inhibits smooth muscle cell migration and reduces neointimal hyperplasia in the rat model of vascular balloon injury[J].Circulation,1999,99:3199.

[4] Rajavashisth TB,Xu XP,Jovinge S,et al. Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques:evidence for activation by proinflammatory mediators [J].Circulation,1999,99:3103.

[5] Luo Z,Sata M,Nguyen T,et al. Adenovirus-mediated delivery of ligand inhibits intimal hyperplasia after balloon injury in immunologically primed animals [J].Circulation, 1999, 99: 1776.

[6] Waltenberger J,Uecker A,Kroll J,et al. A dual inhibitor of platelet derived growth factorβ-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells:a novel candidate for prevention of vascular remodeling[J].Circ Res,1999,85:12.

[7] Numaguchi Y,Naruse K,Harada M,et al. Prostacyclin synthase gene transfer accelerates reendothelializtion and inhibits neointimal formation in carotid arteries after balloon injury[J]. Arterioscler Thromb Vasc Biol,1999,19:1004.

[8 ] Tanada K, Zou JP, Tateda K,et al. Effects of human cytomegalovirus immediate-early protein on p53-mediated apoptosis in coronary artery smooth muscle cells [ J ]. Circulation,1999,99:1656.

[9] Sharma RV,Tan E,Fang S,et al. NOS gene transfer inhibits expression of cell cycle regulatory molecules in vascular smooth muscle cells[J].Am J Physiol(Heart Circ Physiol45),1999, 276:H1450.

[10]Fang S,Sharma RV,Bahlla RC,et al. Enhanced recovery of injury-caused down regulation of paxillin protein by eNOS gene expression in rat carotid artery:mechanism of NO inhibition of intimal hyperplasia[J]?Arterioscler Thormb Vasc Biol,1999, 19:147.

[ 11] Varenne O, Pislaru S, Gillijins H,et al. Local adenovirus-mediated transfer of human endothelial nitric oxide synthase reduces luminal narrowing after angioplasty in pigs [ J ]. Circulation, 1998,98:919-926

备注/Memo

备注/Memo:
收稿日期：2000-08-25.
更新日期/Last Update: 2002-07-01