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|本期目录/Table of Contents|

RAS系统、Ca~(2+)转运与糖尿病心肌病的关系(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2002年第5期
页码:
439-442
栏目:
综述与讲座
出版日期:
2002-09-01

文章信息/Info

Title:
-
作者:
张春虹1;  臧伟进1;  臧益民2
1.西安交通大学医学院心血管生理药理研究室,陕西西安710061;2.第四军医大学生理学教研室
Author(s):
-
关键词:
糖尿病; 心肌病; 肾素-血管紧张素系统; Ca2+; 心肌肥厚; 心肌纤维化
Keywords:
-
分类号:
R544.1
DOI:
-
文献标识码:
A
摘要:
本文在简介肾素-血管紧张素系统和Ca2+通道的基础上,着重综述了它们对糖尿病心肌病的心肌肥大和心肌纤维化的作用。
Abstract:
-

参考文献/References

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[5] Yokoyama T, Sekiguchi K, Tanaka T,et al. AngiotensinⅡ and mechanical stretch induce production of tumor necrosis factor in cardiac fibroblasts[J].Am J Physiol, 1999, 176(6pt2):H1968.

[6] Scheidegger KJ, Dut J, Delafontaine P. Distinct and common pathways in the regulation of insulin-like growth factor-1 receptor gene expression by angiotensinⅡand basic fibroblast growth factor[J].J Biol Chem, 1999, 274 (6): 3522.

[7] Gurantz D, Cowling RT, Villarreal FJ,et al. Tumor necrosis factor-αunregulates angiotensinⅡtype 1 receptors on cardiac fibroblasts[J].Cir Res, 1999,85(3): 272.

[8] Molkentin JD, Lu JR, Antos CL,et al. A calcineurin dependent transcriptional pathway for cardiac hypertrophy[J].Cell, 1998,93:215.

[9] Sussman MA, Lim HW, Gude N,et al. Prevention of cardiac hypertrophy in mice by calcineurin inhibition[J].Science, 1998, 281:1690.

[10] Luika AT, Neil AC, Steffan NH,et al. Rapid shuttling of NF-AT in discrimination of Ca2+signals and immunosuppression [J].Nature, 1996,383:837.

[11] Michael TB, Martin DB, Peten L. Calcium-a lie and death signal[J].Nature, 1998,395:645.

[12] Crabtree GR. Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT[J].Cell, 1999,96:611.

[13] Molkentin JD, Olson EN. GATA4: a novel transcriptional regulator of cardiac hypertrophy? [J] Circulation, 1997,96(11):3833.

[14] Gotzsche LB, Rosenqvist N, Gronbaek H,et al. Increased number of myocardial voltage-gated Ca2+channels and unchanged total beta-receptor number in long-term STZ-diabetic rats [J].Eup J Endocrinol, 1996,134(1):107.

备注/Memo

备注/Memo:
收稿日期：2001-09-20.
更新日期/Last Update: 2002-09-01