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|本期目录/Table of Contents|

恒磁场对兔主动脉内皮细胞增殖的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2002年第6期
页码:
480-481, 484
栏目:
实验研究
出版日期:
2002-11-01

文章信息/Info

Title:
The effects constant magnetic field on the proliferation of rabbit aorta endothelial cells
作者:
张荣庆;  李 飞;  贾国良;  刘 兵;  徐 凯;  赵新国
第四军医大学西京医院心脏内科,陕西西安710032
Author(s):
ZHANG Rong-qing;  LI Fei;  JIA Guo-liang;  LIU Bing;  XU Kai;  ZHAO Xin-guo
Department of Cardiology Xijing Hospital, Fourth Military Medical University, Xi' an,Shaanxi 710032, China
关键词:
恒磁场; 内皮细胞; 增殖
Keywords:
constant magnetic field;  endothelium;  proliferation
分类号:
R363
DOI:
-
文献标识码:
A
摘要:
目的 观察不同剂量恒磁场对兔主动脉内皮细胞增殖影响。方法 将体外培养的3~8代兔主动脉内皮细胞分为对照组及不同剂量(0.5,1,10,100,300,600和1000 Gs,1 Gs=10-4Tesla)磁场组。磁场作用时间为48 h。用3H-TDR法及MTT法测定细胞增殖。结果 与对照组相比,0.5 Gs组细胞增殖显著高于对照组(P<0.05);1 Gs组细胞增殖与对照组相比无明显差异;其余剂量组细胞增殖显著低于对照组(P<0.05)。结论 0.5Gs的恒磁场可以促进兔主动脉内皮细胞的增殖。
Abstract:
AIM To investigated the effects of constant magnetic field(CMF) on proliferation of rabbit aorta endothelial cells(RAEC).METHODS The third to eighth passage RAEC exposed in different magnetic intensity fields including 0.5,1,10,100,300,600 and 1000 Gs for 48 h.. Cell proliferation was measured with3H-TDR and MTT methods.RESULTS Contrasting to control group, the proliferative rate of cells undertaking 0.5 Gs CMF was higher significantly(P< 0.05). There were no difference between 1 Gs group and control group, however cell proliferation was attenuated significantly when CMF intensity was higher than 1Gs(P<0.05).CONCLUSION 0.5 Gs CMF can accelerate proliferation of RAEC.

参考文献/References

[1] Casterella PJ, Teirstein PS. Prevention of coronary restenosis [J].Cardiol Rev, 1999, 7(4):219-231.

[2] Asahara T, Bauters C, Pastore C,et al. Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasis in balloon-injuryed rat carotid artery[J].Circulation, 1995, 91(11): 2793-2803.

[3] Freedman SB, Ismer JM. Therapeutic angiogenesis for coronary artery disease[J].Ann Intern Med, 2002, 136(1):54-71.

[4]曹 丰,贾国良.内皮素与动脉成形术后再狭窄[J].心脏杂志,2001,13(2);146-147.

[5]杨省利,吕安林,贾国良,等.电磁场与恒磁场防治心血管疾病的进展[J].心脏杂志, 2001,13(6);490-492.

[6]冯旭阳,贾国良,赵新国,等.不同强度恒磁场对人脐动脉平滑肌细胞增殖的影响[J].心脏杂志,2002,14(2);113-115.

[7] Epstein SE, Fuchs S, Zhou YF,et al. Therapeutic interventions for enhancing collateral development by admistration of growth factors:basic principles,early resuluts and potential hazards[J].Cardiovasc Res, 2001, 49(3):532-542.

备注/Memo

备注/Memo:
收稿日期：2002-03-06.
更新日期/Last Update: 2002-11-01