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心肌肌浆网钙转运蛋白结构、功能调节及基因表达(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2003年第1期
页码:
64-66
栏目:
综述
出版日期:
2003-01-01

文章信息/Info

Title:
Myocardial SR Ca2+-ATPase structure, functions regulation and gene expression
作者:
李悟 综述李彤杨景学 审校
第四军医大学西京医院心血管外科,陕西 西安 710033
Author(s):
LI Wu LI Tong YANG Jing-xu
Department of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032)
关键词:
肌浆网钙转运蛋白结构功能调节基因表达
Keywords:
SR Ca2+-ATPase structure functions regulation gene expression
分类号:
R651.1
DOI:
-
文献标识码:
A
摘要:
本文简要综述了心肌肌浆网的结构和功能,重点综述钙转运蛋白的结构、功能及其调节和基因表达。
Abstract:
To review the structure and function of myocardial sarcoplasmic reticulum, mainly on the sarcoplasmic reticulum Ca2+-adenosine triphosphatase's structure, function regulation and gene expression.

参考文献/References

[1] 陈群清. 心肌肌浆网Ca2+-ATPase与心肌功能的调控 [J] . 第一军医大学学报, 1999, 19(6):583.

[2] Toyofuko T, Kurzydlowski K, Lytton J, et al. The nucleotide binding/hinge domain plays a crucialrole in determining isoformspecific Ca2+ dependence of organellar Ca2+-ATPases [J] . J Biol Chem, 1999, 267:14490-14496.

[3] MacLennan DH, Clark DM, Loo TW, et al. Site-directed mutagenesis of the Ca2+-ATPase of sarcoplasmic reticulum [J] . Acta Physiol Suppl, 1999, 607:141-150.

[4] Lyton J, Westlin M, Burk SE, et al. Functional comparisons between isoforms of the sarcoplasmic or endiplasmic reticulum family of calcium pumps [J] . J Biol Chem, 2000, 267(20):14483-14489.

[5] Lompre AM, Anger M, Levitsky D. Sarco(endo)plasmic reticulum calcium pump in the cardiovascular system function and gene expression [J] . J Mol Cell Cardiol, 1997, 26:1109-1121.

[6] Hu P, Yin C, Zhang KM, et al. Transcriptional regulation of phospholamban gene produces coordinate expression of these two sarcoplasmic reticulum proteins during skeletal muscle phenotype switching [J] .J Biol Chem, 1999, 271(19):C614-C620.

[7] Odermatt A, Kurzydlowski K, McLennan DH. The Vmax of the Ca2+-ATPase of cardiac sarcoplasmic reticulum (SERCA2a) is not altered by Ca2+/calmodulin dependant phosphorylation or by interaction with phospholamban [J] . J Biol Chem, 1999, 271:14206-14213.

[8] Zador E, Mendler L, VerHeven M, et al. Changes in mRNA levels of the sarcoplasmic/endoplasmic-reticulum Ca2+-ATPase isoforms in the rat soleus muscle regenerating from notexin induced necrosis [J] . Biochem J, 1998, 320:107-113.

[9] Schulte L, Navarro J, Kandarian SC. Regulation of sarcoplasmic reticulum calcium pump expression by hind limb unweighting [J] . Am JPhysiol, 1997, 264 (CellPhysiol33):C617-C622.

备注/Memo

备注/Memo:
收稿日期:2001-10-30.
更新日期/Last Update: 2003-01-01