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|本期目录/Table of Contents|

肥大和衰竭心肌L型Ca2+通道研究进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2003年第3期
页码:
259-261,264
栏目:
综述
出版日期:
2003-05-01

文章信息/Info

Title:
-
作者:
董安平综述; 崔长琮审校
西安交通大学第一医院心血管外科,陕西 西安710061
Author(s):
-
关键词:
L型Ca2+通道; Ca2+诱导的Ca2+释放; 心力衰竭
Keywords:
-
分类号:
R541.6
DOI:
-
文献标识码:
A
摘要:
心肌细胞L型钙电流(ICa·L)触发了Ca2+诱导的Ca2+释放(CICR),调节着细胞内瞬时Ca2+动力学,从而在兴奋-收缩耦联过程中起关键性作用。ICa·L 密度和通道功能的改变参与了心力衰竭的发生。作者综述了:①L型Ca2+通道的结构和生理作用;②肥大和衰竭的心肌ICa·L变化及其频率依赖性调节机制;③Ca2+通道和心力衰竭的治疗关系;④L型Ca2+通道未来研究方向。
Abstract:
-

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2002-2-6.
更新日期/Last Update: 2003-05-01