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可疑冠心病患者肾动脉狭窄发病率及其危险因素的观察(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2004年第1期
页码:
55-56,59
栏目:
临床研究
出版日期:
2004-01-01

文章信息/Info

Title:
The prevalence and associated risk factors of renal artery stenosis in suspected coronary artery disease patients
作者:
李成祥1; 郭新红2; 李虎1; 栾荣华1; 李伟杰1; 秦涛1; 王琼1; 郭文怡1; 贾国良1
1.第四军医大学西京医院心内科,陕西 西安 710032;2.解放军 205医院内四科,辽宁 锦州 121001
Author(s):
LI Cheng-xiang1; GUO Xin-hong2; LI Hu1; LUAN Rong-hua1; LI Wei-jie1; QIN Tao1; WANG Qiong1; GUO Wen-yi1; JIA Guo-liang1
1.Cardiology Department Xijin Hospital, Fourth Military Medical University, Xi'an Shaanxi 710032, China
关键词:
肾动脉狭窄; 发病率; 危险因素; 冠状动脉造影
Keywords:
real artery steosis;  prealece;  risk factors;  coroary angiography
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的:观察可疑冠心病患者肾动脉狭窄(RAS)发病率及其危险因素。方法:对连续184例可疑冠心病患者行冠状动脉造影的同时行肾动脉造影检查,观察该组人群RAS的发病率及危险因素。结果:病理资料完整患者 177例。RAS43例(24.3%),其中狭窄≥50% 22例(12.4%)。冠脉造影正常或轻度病变患者 73例,RAS13例(17.8%),其中狭窄≥50% 5例(6.8%)。冠脉造影异常患者104例 ,RAS30例(28.8%),其中狭窄≥50% 17例(16.3%)。单支、多支病变患者 RAS≥50%分别为 0、17例(21.8%)差异显著(P<0.05)。经单变量和多变量Logistic回归分析,RAS独立预测因子为年龄≥65岁(OR=1.072,95% CI:1.030～1.016,P<0.01)及冠脉多支病变(OR=1.356,95% CI:1.004～1.830,P<0.05)。结论:可疑冠心病患者中,RAS发病率为 24.3%,其中狭窄≥50% 22例(12.4%)。RAS预测因子为老龄及多支冠脉病变。
Abstract:
AIM:To evalate the prealece of agiograpically-determied renal artery steosis(RAS) in suspected coroary artery disease(CHD) patiets who underwent coronary angiografhy, and to identify the risk factors for RAS. METHODS: After coronary angiografhy, abdominal angiography was performed to screen for RAS over 6 months. RESULTS: A total of 177 consecutive patients (male 131,famale 46),with the mean age of 57.5±11.0 years were stdied.RAS was found in 43 patients(24.3%),including 22(12.4%) with siginificant stenosis (≥50%).73 were with normal coronary angiogram or non-significant CHD,13(17.8%) had RAS,including 5 (6.8%) with significant stenosis. In 104 patients with angiographically significant CHD, 30 (28.8%) had RAS, including 17 (16.3%) with signidicant stenosis, Significant RAS were found in 0 and 17 (21.8%) patients with single-and multi-vessel diseases, respectively. By univariate and multivariable logistic regression analysis, the association of clinical variables with RAS was assessed. Multivaiable predictors included age(≥65years)(OR=1.072,95%CI:1.030～1.016,P<0.001) and multi-vessel disease (OR=1.356,95%CI:1.004～1.830,P<0.05). CONCLUSION: Sigiicat RAS was found in 12.4% of the patients with suspected CHD. Old age and multi-vessel disease were the predictors for RAS.

参考文献/References

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[3]杨进刚,胡大一,刘昆申,等.冠状动脉造影患者中肾动脉狭窄的发生率[J].中华内科杂志,2002,41(1):24-27.

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备注/Memo

备注/Memo:
收稿日期：2003-3-4
更新日期/Last Update: 2004-01-01