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|本期目录/Table of Contents|

依普利酮治疗心力衰竭的研究进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2005年第2期
页码:
152-153
栏目:
综述
出版日期:
2005-03-05

文章信息/Info

Title:
-
作者:
方志敏 徐佩茹徐秦张爱伦
新疆医科大学第一附属医院,新疆 乌鲁木齐830054
Author(s):
-
关键词:
-
Keywords:
-
分类号:
R541.6
DOI:
-
文献标识码:
A
摘要:
本文概述了选择性醛固酮拮抗剂Eplerenone(Epl,依普利酮)的药理学特性、治疗心力衰竭(HF)的作用机制及随机对照试验和副作用。
Abstract:
-

参考文献/References

[1] 臧益民,臧伟进,王晓明. 心力衰竭的病理生理机制及治疗概述[J]. 心脏杂志,2002,14(5):413-419.

[2] Sharon A,David W,Marshall H,et al. ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult[J]. Circulation, 2001, 104:2996.

[3] Adams KF Jr. Pathophysiologic role of the renin angiotensin aldosterone and sympathetic nervous systems in heart failure[J]. Am J Health Syst Pharm,2004,61 (Suppl 2):S4-S13.

[4] Nancy J, Brown MD. Eplerenone cardiovascular protection[J]. Circulation, 2003, 107: 2512-2518.

[5] Moore TD, Nawarskas JJ, Anderson JR. Eplerenone: a selective aldosterone receptor antagonist for hypertension and heart failure[J]. Heart Dis, 2003, 5(5):354-363.

[6] Stier CT Jr, Koenig S, Lee DY, et al. Aldosterone and aldosterone antagonism in cardiovascular disease: focus on eplerenone (Inspra)[J]. Heart Dis, 2003, 5(2):102-118.

[7] Khan NU, Movahed A. The role of aldosterone and aldosterone receptor antagonists in heart failure[J]. Rev Cardiovasc Med, 2004,5(2):71-81.

[8] Struthers AD, MacDonald TM. Review of aldosterone and angiotensin IIinduced target organ damage and prevention[J]. Cardiovasc Res,2004,61(4):663-670.

[9] Pitt B, Remme W, Zannad F, et al. Eplerenone postacute myocardial infarction heart failure efficacy and survival study investigators. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction[J]. N Engl J Med, 2003,348(14):13091321.

备注/Memo

备注/Memo:
收稿日期:2004-09-20.
更新日期/Last Update: 2010-01-05