高血压病患者脑血管血流动力学指标的观测(PDF)
《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]
- 期数:
- 2005年第3期
- 页码:
- 246-248
- 栏目:
- 临床研究
- 出版日期:
- 2005-05-05
文章信息/Info
- Title:
- A contrast study on cerebral vascular hemodynamic parameters in hypertension patients
- 作者:
- 郑竞
- 福建省立医院健康体检中心，福建 福州 350001
- Author(s):
- ZHENG Jing
- 1. Department of cardiology, Shanxi Lvliang Rongjun Hospital, Lishi,Shanxi 033000, China
- Keywords:
- hypertension; hemodynamic; cerebral vascular disease
- 分类号:
- R743；R541.3
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 目的 观测和分析高血压病患者脑血管血流动力学指标的变化特征。方法 在门诊患者或体检人群中选择单纯高血压病患者91例，同时选择血压正常者92例（对照组），进行脑血管血流动力学指标（CVHP）检测，并以统一的方法计算脑血管功能积分。比较两组间CVHP及脑血管功能积分的差异。结果 高血压病组脑血流量、平均脑血流速度、最大脑血流速度、最小脑血流速度、舒张压与临界压差值，显著低于对照组（P<0.05）；外周阻力、特性阻抗、脉搏波波速、动态阻力、临界压显著高于对照组(P<0.05)。高血压病组和对照组的脑血管功能积分分别为81±26和94±13（P<0.01）。结论 高血压病患者的CVHP普遍呈现异常改变，脑血流量、血流速度和脑血管功能积分降低，血管阻力和阻抗等指标升高。
- Abstract:
- AIM To probe into characteristics of cerebral vascular hemodynamic parameters(CVHP) change in hypertension patients. METHODS Participants were selected from outpatients and medical examination individuals. 92 hypertension patients and 91 normal individuals were enlisted in the study. Subjects of both groups were free of other risk factors of stroke. All of participants received checkup of CVHP and cerebral vascular function scores(CVFS) were estimated according to CVHPs. Differences in CVHPs and CVFSs were compared. RESULTS CVHPs such as Qmean, Vmean, Vmax, Vmin and DP in the hypertension group were significantly lower than those in the control group(P<0.05). However, Rv, Zcv, WV, DR, CP were significantly higher than those of the controls(P<0.05). CVFSs between the two group were also significantly different and the means were 81±26 and 94±13 respectively（P<0.01）. CONCLUSION CVHP in hypertension patients usually undergoes abnormal changes which is characterized as the decrease in cerebral blood quantity, velocity, CVFS and increase in resistance and impedance.
参考文献/References
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［3］Chiu JJ, Chen LJ, Chen CN, et al. A model for studying the effect of shear stress on interactions between vascular endothelial cells and smooth muscle cells［J］. J Biomech, 2004,37(4):531-539.
［4］ 杨渤生，王桂清，王艳. 从正常人到脑卒中患者的不同人群的脑血管血液动力学变化规律［J］. 中华流行病学杂志，2003,24(2):94-97.
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［6］ 黄久仪，郭佐，沈风英,等. 脑血管血流动力学预警卒中的筛检试验评价［J］. 中华流行病学杂志，2002，23（5）：383-386.
备注/Memo
- 备注/Memo:
- 收稿日期：2004-06-07.
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更新日期/Last Update: 2010-01-05