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老年原发性高血压并发冠心病患者血压昼夜节律及心率变异性的变化(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2005年第6期
页码:
581-582,585
栏目:
临床研究
出版日期:
2005-12-05

文章信息/Info

Title:
Variability of circadian rhythm of blood pressure and heart rate in aged patients with essential hypertension complicated with coronarydisease
作者:
任春霖; 李东峰
郧阳医学院附属东风公司总医院心内科, 湖北 十堰 442008
Author(s):
REN Chunlin;  LI Dongfeng
Department of Cardiology, General Hospital of Dongfeng Automobile Company, Yun Yang Medical College,Shiyan,Hubei 442008，China
关键词:
冠状动脉疾病; 高血压; 原发性; 昼夜节律; 心率变异性
Keywords:
coronary disease; hypertension; circadian rhythm; heart rate variability
分类号:
R544.1
DOI:
-
文献标识码:
A
摘要:
目的 观察老年原发性高血压并发冠心病患者动态血压昼夜节律及心率变异性的变化。 方法 按有无冠心病将老年原发性高血压患者分为两组，A组为原发性高血压并发冠心病组，B组为原发性高血压组，进行24 h无创动态血压及动态心电图监测。结果 老年原发性高血压并发冠心病患者夜间收缩压明显升高(P<0.01),其血压昼夜差值、节律变化、以及夜间血压及心率下降幅度较单纯原发性高血压患者明显减小，心率变异性明显降低。结论 原发性高血压患者并发冠心病时患者血压的昼夜变化减小，提示自主神经的调节功能受损。
Abstract:
AIM To observe the variability of circadian rhythm of blood pressure and heart rate in aged patients with essential hypertension (EH) complicated with coronary heart disease (CHD). METHODS The aged EH patients complicated with CHD were enrolled in group A and those without CHD were in group B. 24hour dynamic electrocardiogram and blood pressure monitoring were performed on all patients. RESULTS In group A, the systolic blood pressure at night increased significantly (P<0.01), and variability of blood pressure and heart rate were more obvious compared with group B. CONCLUSION The impairment of regulatory activity of circadian blood pressure and autonomic nerve is more severer in EH patients with CHD than in those without CHD.

参考文献/References

［1］ 李荣,严钟德,刘东方. 糖尿病患者心自主神经功能与24小时动态血压变化的探讨［J］. 中国糖尿病杂志,2000,8:17-20.

［2］ Cirillo M,Stellato D,Laurenzi M,et al. Pulse pressure and isolated systolic hypertension:association with microalbuminuria. The GUBBIO Study Collaborative Research Group［J］. Kidney Int,2000,58:1211-1218.

［3］ 张录兴，郑强荪，许新录，等. 冠心病患者心率变异性昼夜变化观察［J］. 心脏杂志，2003，2：185.

［4］ 方业明，齐连方，李川杰，等. 老年糖尿病并发原发性高血压患者24小时血压昼夜节律变化［J］. 中华老年心血管病杂志，2004，3：167.

备注/Memo

备注/Memo:
收稿日期：2005-03-15.作者简介：任春霖，主治医师，学士Tel:(0719)8272345，Email:rcl640318@126.com
更新日期/Last Update: 2010-01-06