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冠状动脉内直接支架术对无复流现象的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2006年第1期
页码:
74-75
栏目:
临床研究
出版日期:
2006-01-01

文章信息/Info

Title:
Effect of direct coronary stenting on noreflow phenomena in patients with coronary artery disease
作者:
黄定; 马依彤; 张宇; 杨毅宁; 再帕尔; 王疆; 刘晓; 王新华
新疆医科大学第一附属医院心血管病专科医院，新疆 乌鲁木齐 830054
Author(s):
HUANG Ding;  MA Yi-tong;  ZHANG Yu;  YANG Yi-ning;  ZAI Pa-er;  WANG Jiang;  LIU Xiao;  WANG Xing-hua
First Affilated Hospital of Xinjiang Medical University, Urumqi， Xinjiang 830054，China
关键词:
冠状动脉支架术; 无复流现象; 直接支架术
Keywords:
coronary stenting;  no reflow;  direct stenting
分类号:
R543.3
DOI:
-
文献标识码:
A
摘要:
目的 评价冠心病患者冠状动脉内直接支架术对术后无复流的影响。方法 入选239例接受冠脉内直接支架术的患者(直接支架组)和239例球囊预扩张后行冠脉支架术的患者(常规支架组),分析两组患者的术中无复流现象发生率，并观察住院期间主要不良心血管事件发生率。结果 直接支架组术后无复流发生率 (8.8%)低于常规支架组(19.2%,P<0.01)，直接支架术组主要心血管事件发生率也较低(6.7% vs 13.4%,P<0.01)。结论 冠脉内直接支架有助于降低冠心病患者无复流现象和不良心血管事件发生率。
Abstract:
AIM To compare the effect of direct stenting (DS) and conventional postdilation stenting (CS) on noreflow phenomena in patients with coronary artery disease (CAD) . METHODS The noreflow rates and major cardiac events were compared between patients receiving DS (n=239) and those receiving CS (n=239). RESULTS The noreflow rate of DS group (8.8%) was lower than that of CS group ( 8.8% vs 19.2%,P<0.01). Patients in DS group had lower major cardiac events rates than those in CS group(6.7% vs 13.4%,P<0.01). CONCLUSION DS can reduce both noreflow rate and MACE rate in CAD patients.

参考文献/References

［1］Wainstein M, Frederic F, Lee M, et al. Lack of clinical efficacy of pharmacologic treatment of the noflow phenomenon despite significant angiographic improvement［J］. J Am Coll Cardiol, 2001, 37(2): 83A.

［2］Sakuma T, LeongPoi H, Fisher NG, et al. Further insights into the noreflow phenomenon after primary angioplasty in acute myocardial infarction: the role of microthromboemboli［J］. J Am Soc Echocardiogr, 2003, 16:15-21.

［3］David A, Renato V, Angela M, et al. Direct infarct artery stenting without predilation and noreflow in patients with acute myocardial infarction［J］. Am Heart J, 2001, 142: 684-690.

［4］Sabatier R, Hamon M, Zhao QM, et al. Could direct stenting reduce noreflow in acute coronary syndromes? A randomized pilot study［J］. Am Heart J, 2002, 143: 1027-1032.

［5] Atmaca Y, Altin T. Ozdol SC, et al. Direct stent implantation in acute coronary syndrome［J］. J Invasive Cardiol, 2002, 14: 308-312.

［6］Resnie FS, Wainstein M, Lee MK, et al. Noreflow is an independent predictor of death and myocardial infarction after percutaneous coronary intervention［J］. Am Heart J, 2003, 145: 42-46.

备注/Memo

备注/Memo:
收稿日期：2005-07-11.通讯作者：黄定，副主任医师，副教授，主要从事冠心病介入治疗研究 Tel:(0991)4362616
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