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|本期目录/Table of Contents|

CD40-CD40L与急性冠脉综合征的研究进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2006年第2期
页码:
239-241
栏目:
综述
出版日期:
2006-03-01

文章信息/Info

Title:
-
作者:
周启林 田国平
南华大学附属第二医院心内科,湖南 衡阳 421001
Author(s):
-
关键词:
CD40 CD40L 冠脉综合征急性 抗CD40L抗体
Keywords:
-
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
本文介绍了CD40与CD40L的生物学特性,包括其分布、来源、信号转导机制。综述了CD40CD40L与慢性炎症、免疫调节、血栓形成、斑块不稳定的相关性,提示抗CD40L治疗是未来防治急性冠脉综合征的一个方向。
Abstract:
-

参考文献/References

[1]Schonbeck U,Mach F,Libby P.CD154(CD40 ligand)[J]. Int J Biochem cell Biol,2000,32:687-693.

[2] Jabara HH,Brodeuer SR,Geha RS.Glucocorticoids upregulate CD40 ligand expression and CD40Ldependent immunoglobulin isotype switching[J]. J Clin Invest,2001,107:371-378.

[3] Heeschen C,Dimmeler S,Hamm CW,et al.Soluble CD40 ligand in acute coronary syndromes[J]. N Engl J Med, 2003,348(12):1104-1111.

[4]Melter M,Reinders ME,Sho M,et al.Ligation of CD40 induces the expression of vascular endothelial growth factor by endothelial cells and monocytes and promotes angiogenesis in vivo[J]. Blood,2000,96(12):3801-3808.

[5]Uibich C ,Dernbach E,Aicher A,et al.CD40 ligand inhibits endothelial cell migration by increasing production of endothelial reactive oxygen species[J]. Circulation,2002,106(8):981-986.

[6]Schonbeck U,Sukhova GK,Shimizu K,et al.Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice[J].Proc Natl Acad Sci U S A,2004,97 (13):7458-7463.

[7]Andre P,Prasad KS,Denis CV,et al.CD40L stabilizes arterisl thrombi by a beta 3 integrindependent mechanism[J]. Nat Med,2002,8(3):247-252.

[8]蒋晖,李锦,毛建斌,等. 同型半胱氨酸对内皮细胞CD40L表达的影响[J].心脏杂志,2004,16(5):431-433.

[9] Garlichs CD,John S,Schmeisser A,et al.Upregulation of CD40 and CD40 ligand (CD154)in patients with moderate hypercholesterolemia[J]. Circulation,2001,104(20):2395-2400.

[10]曾知恒,吴海珊.急性冠状动脉综合征患者血清sCD40L和血浆sICAM1,sEselectin关系的研究[J].广西医学,2004,26(11):1593.

[11]Krotz F,SchieleTM,Zahler S,et al.Sustained platelet activation following intracoronary beta irradiation[J]. Am J Cardiol, 2002,90(12):1381-1384.

[12]Schonbeck U,Varo N,Libby P,et al.Soluble CD40L and cardiovascular risk in women[J]. Circulation, 2001,104(19):2266-2268.

[13]曾武涛,冷秀玉,王礼春,等. 可溶性CD40L对急性冠脉综合征患者近期预后的影响[J].中华心血管病杂志,2004,32(11):1043.

[14]Wagner AH,Gebauer M,Guldenzoph B,et al.3hydroxy3methylglutaryl coenzyme A reductaseindependent inhibition of CD40 expression by atorvastatin in human endothelial cells[J] . Arterioscler Thromb Vasc Biol, 2002,22(11):1784-1789.

备注/Memo

备注/Memo:
收稿日期:2005-06-08.作者简介:周启林,硕士 Tel:(0734)8288966 Email:zhouqilin1978@126.com
更新日期/Last Update: