我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

小鼠腹腔异位心脏移植技术的改良(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2006年第4期
页码:
411-413
栏目:
基础研究
出版日期:
2006-08-25

文章信息/Info

Title:
Improved technique of heterotopic abdominal heart transplantation in mice
作者:
李伟栋; 倪一鸣; 冯强
浙江省器官移植中心，浙江大学医学院附属第一医院心胸外科，浙江 杭州 310003
Author(s):
LI Wei-dong;  NI Yi-ming;  FENG Qiang
Centre of Organ Transplantation, Department of Cardiothoracic Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou，Zhejiang 310003, China
关键词:
小鼠; 动物模型; 异位心脏移植
Keywords:
mouse;  animal model; heart transplantation;  heterotopic
分类号:
R654.2
DOI:
-
文献标识码:
A
摘要:
目的 探讨小鼠腹腔异位心脏移植技术的改进。方法 参考大鼠心脏移植Ono式模型，并在供心摘取、血管吻合区准备和血管吻合技术上加以改良，建立小鼠心脏异位腹腔移植模型。结果 改良后的心脏移植模型简化了手术操作，减少了供心的总缺血时间，手术成功率达到了90%。结论 采用新方法可提高小鼠腹腔异位心脏移植成功率。
Abstract:
AIM To improve on the technique of heterotopic abdominal heart transplantation in mice. METHODS Based on the Ono's transplantation model technique, we were to establish a heterotopic abdominal heart transplantation model in mice by improving the technique of donor operation and quality of blood vessel anastomosis. RESULTS The heterotopic heart transplantation model in mouse was successfully established with mean hot ischemia and cold ischemia（1.1±0.4）min and （35.8±1.7）min, respectively and a success rate of 90%. CONCLUSION Our newly established murine model of heterotopic heart transplantation is stable and reliable.

参考文献/References

［1］ Zhong R. Organ transplantation in mice: current status and future prospects［J］. Microsurgery,1999,19(2):52-55.

［2］ Ono K, Lindsey ES. Improved technique of heart transplantation in rats［J］. J Thorac Cardiovasc Surg, 1969,57(2):225-229.

［3］ Tomita Y, Zhang QW, Yoshikawa M,et al. Improved technique of heterotopic cervical heart transplantation in mice［J］. Transplantation, 1997,64(11):1598-1601.

［4］ Billingham ME, Cary NR, Hammond ME, et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: heart rejection study group. The international society for heart transplantation［J］. J Heart Transplant,1990,9(6):587-593.

［5］ Ensminger SM, Billing JS , Morris PJ , et al. Development of a combined cardiac and aortic transplant model to investigate the development of transplant arteriosclerosis in the mouse［J］. J Heart Lung Transplant,2000,19(11):1039-1046.

［6］ Tomita Y，Zhang QW，Yoshikawa M,et al. Impmved technique of hetero topic cervical heart transplantation in mice［J］. Transplantation,1997,64(11):1598-1601.

［7］ Qian SG, Fung JJ, Demetris AV,et al. Orthotopic liver transplantation in the mouse［J］. Transplantation, 1991,52(3):562-564.

备注/Memo

备注/Memo:
收稿日期：2005-05-20.基金项目：浙江省自然科学基金项目资助（No.491010-N20086） 作者简介：李伟栋，住院医师，硕士 Email：smallangellwd@eyou.com
更新日期/Last Update: