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左旋卡尼汀能有效提高稳定型心绞痛患者的运动耐量 (PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2006年第4期
页码:
442-444
栏目:
临床研究
出版日期:
2006-08-25

文章信息/Info

Title:
L-carnitine effectively improves exercise tolerance in patients with stable angina pectoris
作者:
殷仁富1; 张治宇1; 时慧琦1; 陈金明1; 顾书华2; 宋森涛2
1.第二军医大学长征医院心内科，上海 200003；2. 常州三维工业技术研究所，江苏 常州 213000
Author(s):
YIN Ren-fu;  ZHANG Zhi-yu;  SHI Hui-qi;  CHEN Jin-ming;  GU Shu-hua;  SONG Sen-tao
Department of Cardiology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
关键词:
心绞痛; 运动耐量; 心肌代谢
Keywords:
angina pectoris;  exercise tolerance;  myocardial metabolism
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 观察国产左旋卡尼汀（L-CN）对稳定型心绞痛患者临床症状和运动耐量的影响。方法 在常规治疗的基础上使用L-CN辅助治疗稳定型心绞痛患者80例，40例患者作为对照。记录两组患者治疗前后临床症状、心电图、心功能、运动试验心电图。结果 L-CN可以明显缓解患者心绞痛临床症状，改善心功能，并显著提高运动耐量和心绞痛负荷阈值。结论 L-CN是心绞痛代谢治疗的有效药物之一。
Abstract:
AIM To investigate the effect of L-carnitine (L-CN) on the clinical symptoms and exercise tolerance in patients with stable angina pectoris. METHODS Clinical symptoms, ECG, heart function and exercise tolerance of 80 patients with stable angina pectoris were measured before and after they received L-CN 3.0 g intravenous infusion per day for 21 d, and 40 other patients were included as control. RESULTS L-CN alleviated clinical symptoms, and improved heart function and exercise tolerance of patients. CONCLUSION L-CN is one of the effective metabolitic drugs for stable angina pectoris.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2005-03-11.基金项目：全军“十五”面上科研基金项目资助(No.01M002) 作者简介：殷仁富，教授 Tel：（021）63617082
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