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|本期目录/Table of Contents|

代谢综合征患者颈动脉粥样硬化的观察(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2006年第4期
页码:
451-453
栏目:
临床研究
出版日期:
2006-08-25

文章信息/Info

Title:
Observation of carotid atherosclerosis in metabolic syndrome patients
作者:
刘松岩1; 韩凤英2; 马 杰1
1.武警新疆总队医院急诊科, 新疆 乌鲁木齐 830091;2.解放军474医院, 新疆 乌鲁木齐 830011
Author(s):
LIU Song-yan;  HAN Feng-ying;  MA Jie
Department of Emergency, Xinjiang Uygur Autonomous Region Corps Hospital, Chinese People′s Armed Police Forces, Urumqi,Xinjiang 830091, China
关键词:
代谢综合征; 高血压; 原发性; 颈动脉; 动脉粥样硬化
Keywords:
metabolic syndrome;  essential hypertension;  diabetes mellitus;  atherosclerosis
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 探讨代谢综合征（MS）患者颈动脉粥样硬化的特征。方法 108例患者分别为MS 40例、高血压病(EH)33例、糖尿病(DM)35例，并以此相应分成3组，比较3组患者血脂改变及颈动脉超声检测结果，以125例健康体检者作对照组。结果 MS组和DM组患者血浆TG水平均明显升高。DM组和MS组颈动脉阻力指数均显著升高，3组颈总动脉内中膜厚度明显增厚。MS组患者斑块指数较单纯EH组明显增高。结论 MS患者发生颈动脉粥样硬化的危险性较单纯高血压组明显增加。
Abstract:
AIM To observe the carotid atherosclerosis in metabolic syndrome (MS). METHODS One hundred and eight patients were divided into three groups: MS group, typeII DM group and essential hypertension (EH) group. Plasma lipids detection and ultrasonography for carotid artery were conducted. One hundred and twenty five healthy subjects under routine physical checkup were enrolled as control. RESULTS The level of TG was significantly higher in MS and DM groups. The carotid resistant index was significantly higher in MS and DM groups and the intimamedia thickness of common carotid artery increased in all the three groups. Plaque index in MS group was higher than that in EH group. CONCLUSION The patients with metabolic syndrome are more susceptible to carotid atherosclerosis.

参考文献/References

［1］ Grundy SM, Brewer HB Jr, Cleeman JI, et al. Definition of metabolic syndrome report of the national heart, lung, and blood institute/american heart association conference on scientific issues related to definition［J］. Circulation, 2004,109(3):433-438.

［2］ Ford ES, Giles WH, Diets WH. Prevalence of the metabolic syndrome among US adults: findings from the third national health and nutrition examination survey［J］. JAMA, 2002, 287(3):356-359.

［3］ Salonen JT, Salonen R. Ultrasound Bmode imaging in observational studies of atherosclerotic progression［J］. Circulation, 1993,87(3 Suppl):Ⅱ56-Ⅱ65.

［4］ National cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III ) . Third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III ) final report［J］. Circulation, 2002, 106(25):3143-3421.

［5］ Abbasi F, Brown BW Jr, Lamendola C, et al. Relationship between obesity, insulin resistance, and coronary heart disease risk［J］. J Am Coll Cardiol, 2002, 40(5): 937-943.

［6］ 刘松岩,杨欣国,马岩萍,等. 冠状动脉病变长度的相关因素［J］. 心脏杂志，2004,16(6):545-549.

［7］ 刘静, 赵冬,王薇,等. 中国多省市心血管疾病危险因素的队列研究与美国弗莱明翰心脏研究结果的比较［J］. 中华心血管病杂志,2004,32(2):167-172.

备注/Memo

备注/Memo:
收稿日期：2005-03-17.作者简介：刘松岩，副主任医师 Tel：（0991）8025326 Email：Lsy@haouosheng.com
更新日期/Last Update: