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|本期目录/Table of Contents|

在小儿胸腔镜引导纤维软镜下右室流出道手术的动物实验研究(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2007年第5期
页码:
535-537
栏目:
基础研究
出版日期:
2007-10-01

文章信息/Info

Title:
Animal experiment for right ventricle outflow tract surgery under infant fibrothracoscope leading
作者:
王显悦; 俞世强; 杨剑; 陈涛; 李杨; 徐学增
第四军医大学西京医院心血管外科，陕西 西安 710032
Author(s):
WANG Xianyue;  YU Shiqiang;  YANG Jian;  CHEN Tao;  LI Yang;  XU Xuezeng
Center of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi′an 710032, Shaanxi, China
关键词:
动物实验; 纤维胸腔软镜; 犬
Keywords:
animal experiment; fibrothracoscope; dog
分类号:
R561
DOI:
-
文献标识码:
A
摘要:
目的 研究在小儿胸腔镜引导纤维软镜下，右室流出道畸形矫治的动物手术方法。方法 选用心肺功能良好的杂种犬各30只，分别为实验组和对照组，其中实验组按手术前后顺序又分为A、B、C 3组。实验组进行胸腔镜引导纤维软镜体外循环下模拟右室流出道畸形解除手术；对照组进行胸腔镜体外循环下房间隔缺损修补手术。分别记录两组的平均动脉压、中心静脉压和心率；实验组还记录手术时间、主动脉阻闭时间和转机时间。结果 手术过程中，实验组与对照组不同时段的平均动脉压、中心静脉压和心率均无显著差异。经过练习后，与A组相比，C组手术时间、主动脉阻闭时间和转机时间均显著缩短（P<0.05）。结论 胸腔镜引导纤维软镜下进行右室流出道的动物手术是安全可行的，手术时间与镜下操作的熟练程度有关。
Abstract:
AIM To investigate the operation method for corrective therapy of right ventricle outflow tract deformity under infant fibrothracoscope leading. METHODS Sixty dogs with satisfactory heart and lung functions were employed in this study. In control group (n=30), the repair of atrial septal defect was carried out by extracorporeal circulation under thoracoscope, while in experiment group (n=30), the corrective operation of right ventricle outflow tract deformity was conducted by extracorporeal circulation under fibrothracoscope leading. Experiment group subdivided into three groups, namely A, B and C based on sequence before and after operation. Mean arterial pressure, central venous pressure and heart rate in both groups were recorded respectively. The operating time, aortic blocking time and cardiopulmonary bypass time were also recorded in the experiment group. RESULTS There was no significant difference between experiment group and control group in mean arterial pressure, central venous pressure and heart rate. After practice, the operating time, aortic blocking time and cardiopulmonary bypass time in the group C were notably shorter than those in the group A. CONCLUSION The animal operation of right ventricle outflow tract surgery under fibrothracoscope leading is safe and feasible. Operating time is related to the surgeon′s dexterity under fibrothracoscope.

参考文献/References

［1］俞世强，蔡振杰，程云阁，等.胸腔镜下室间隔缺损修补术［J］.中国微创外科杂志，2002，2（5）：288-289.

［2］段大为，刘维永，朱海龙，等.电视胸腔镜在小儿心脏手术中的应用［J］.中国内镜杂志，2003，9（8）：7-8，11.

［3］陈文彬，戢朝明，李又环，等.经纤维支气管镜肺活检对弥漫性及周围性肺病变的诊断价值［J］.中华内科杂志，1989,28(9):559-560.

［4］王永碧，林兮，赵甫成，等.纤支镜代替胸腔镜检查术对胸膜疾病的诊断体会［J］.中国内镜杂志,2001，7(3):74.

［5］段大为，俞世强，陈德凤，等.电视胸腔镜辅助下房间隔缺损修补术36例报告［J］. 中国微创外科杂志，2002，2（5）:290-291.

［6］王宏山，申红亚，李凯，等.胸腔镜下胸壁打孔房间隔缺损修补术35例报告［J］.中原医刊，2003，30（14）:18.

备注/Memo

备注/Memo:
收稿日期：2007-03-09.基金项目：国家科技攻关项目资助（No.2004BA720A12）通讯作者：徐学增，博士，主要从事微创功能心脏外科临床研究Email：xuxuez@fmmu.edu.cn 作者简介：王显悦，硕士Email：nnnd@hotmail.com
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