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|本期目录/Table of Contents|

老年心力衰竭患者外周血红细胞膜脂流动性的变化及与心功能的相关性(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2007年第6期
页码:
707-708/712
栏目:
临床研究
出版日期:
2007-12-20

文章信息/Info

Title:
Changes of membrane lipid fluidity of erythrocytes in elderly patients with congestive heart failure
作者:
唐发宽; 华宁; 张同欣; 钮炜西; 陆宏; 肖军; 唐雪正; 王龙
解放军总医院第二附属医院心内科，北京 100091
Author(s):
TANG Fa-kuan;  HUA Ning;  ZHANG Tong-xin;  NIU Wei-xi;  LU Hong;  XIAO Jun;  TANG Xue-zheng;  WANG Long
Department of Cardiology, Second Hospital of PLA General Hospital, Beijing 100091, China
关键词:
心力衰竭 ; 充血性; 膜脂流动性; 红细胞
Keywords:
heart failure; congestive; lipid fluidity; erythrocytes
分类号:
R541.6;R287.972
DOI:
-
文献标识码:
A
摘要:
目的 观察红细胞膜脂流动性（LFU）在老年充血性心力衰竭（CHF）中的变化及其意义。方法 选择CHF患者40例，正常对照者30例，用荧光分光光度计偏振技术测定外周血红细胞LFU。结果 CHF组红细胞LFU明显低于正常对照组（P<0.01)；心功能越差，LFU越低（P<0.05和P<0.01）。结论 红细胞LFU在一定程度上反映了CHF程度。
Abstract:
AIM To explore the changes of 1ipid fluidity (LFU)of erythrocytes membrane in elderly patients with congestive heart failure (CHF). METHODS Retrospective study was carried out to measured the LFU of erythrocytes membrane in the peripheral blood of 40 patients with CHF and 30 contro1s by fluorescence po1arization analysis. RESULTS The LFU of erythrocytes in CHF was apparently decreased compared with that in contro1（P<0.01）. The worse was the cardiac function, the lower was the LFU value of erythrocytes（P<0.05 and 0.01，at 7th day and 21st day after hospitalization). CONCLUSION The decrease of the LFU of erythrocytes membrane in peripheral blood may reflects the severity of CHF to some extent.

参考文献/References

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［9］ 许艳,高佩琦,马波,等. 急性脑梗塞的红细胞膜流动性及生化指标改变［J］.哈尔滨医科大学学报,2000,34（1）:24-25.

备注/Memo

备注/Memo:
收稿日期：2007-03-12.作者简介：唐发宽，主任医师，硕士 Email:TFK616@yahoo.com.cn
更新日期/Last Update: