心房颤动对心力衰竭患者预后的影响(PDF)
《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]
- 期数:
- 2008年第1期
- 页码:
- 87-88，94
- 栏目:
- 临床研究
- 出版日期:
- 2008-01-20
文章信息/Info
- Title:
- Effect of atrial fibrillation on longterm prognostic factors in patients with heart failure
- Author(s):
- CHEN Zhishu1; CHEN Zhiyue2; XIN Suping1; SHEN Yaping1
- 1.Wujin Hospital, Jangsu University, Changzhou 213002, Jiangsu, China; 2.Second Hospital of Ningbo City, Ningbo 315010, Zhejiang, China
- 分类号:
- R541.75
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 目的 探讨心房颤动（AF）对心力衰竭（HF）患者远期预后的影响。方法 回顾性研究63例HF患者，根据HF是否并发AF的临床特点：分有AF组(A组)，无AF组(B组)，并随访（23±8）月，观察AF对HF远期不良事件发生及预后的影响。结果 ①左心房内径，A组大于B组 ［(49±8)mm vs (43±7)mm，P<0.05］；左心室射血分数，A组低于B组 ［(33±5)% vs (42±6)%，P<0.05］； ②脑栓塞发生率，A组高于B组 (26% vs 6%，P<0.05)； ③快速性心律失常，A组高于B组( 77% vs 47%，P<0.05)； ④不良事件发生：A组因HF加重或脑栓塞发生的再住院率高于B组（P<0.01）； ⑤病死率：A组多于B组 (32% vs 13%，P<0.01)。结论 HF基础上发生AF，预示着对原发性心脏疾病的远期不良事件发生增多，预后影响较大。
- Abstract:
- AIM To explore the effect of atrial fibrillation (AF) on longterm prognostic factors in patients with heart failure (HF). METHODS Sixtythree patients were divided into AF group (group A) and nonAF group (group B) and their clinical outcomes were followed up for 23±8 months. RESULTS ① The left cardiac atrium inner diameter in group A was larger than that in group B ［(49±8)mm vs (43±7)mm, P<0.05］ and the left ventricular ejection fraction in group A was lower than that in group B ［(33±5)% vs (42±6)%, P<0.05］ ② The incidence of cerebral embolism in group A was higher than that in group B (26% vs 6%, P<0.05） ③ The ventricular rate and ventricular tachyarrhythmia in group A were higher than those in group B (77% vs 47%, P<0.05) ④ Group A, due to HF aggravation or cerebral embolism, had higher rehospitalization rate than group B (46 vs 29, P<0.01）⑤ The death rate in group A was higher than that in group B (32% vs 13%，P<0.01). CONCLUSION Atrial fibrillation in patients with heart failure enhances the risk of primary heart disease, influences the prognosis and increases the disability rate and death rate.
参考文献/References
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［6］ Cugno M, Mari D, Meroni PL, et al. Haemos tatic and inflammatory biomarkers in advanced chronic heart failure : role of oral anticoagulants and successful heart Transplantation ［J］ .Briheamatol,2004,126(1):85-92.
［7］ Benjamin EJ, Wolf PA, D’Agostino RB, et al. Impact of atrial fibrillation on the risk of death: the Framingham Heart Study ［J］. Circulation, 1998 ,98(10):946-952.
［8］ Caro JJ, Flegel KM, Orejuela ME, et al. Anticoagulant prophylaxis against stroke in atrial fibrillation: effectiveness in actual pratice ［J］. CMAJ, 1999,161(19):493-497.
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备注/Memo
- 备注/Memo:
- 收稿日期：2006-10-17.作者简介：陈志术，副主任医师Email：mnkbtcxc@126.com
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