我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

应用应变及应变率技术评价心力衰竭患者左心室功能(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2008年第2期
页码:
166-168
栏目:
临床研究
出版日期:
2008-03-20

文章信息/Info

Title:
Evaluation of left ventricular function using strain and strain rate in patients with heart failure
作者:
吴红宁; 李滨滨
南京市胸科医院医学影像二科，江苏 南京，210029
Author(s):
WU Hongning;  LI Binbin
Department of Medical Imaging, Nanjing Chest Hospital, Nanjing 210029，Jiangsu, China
关键词:
心力衰竭; 应变; 应变率
Keywords:
heart failure ;  strain ;  strain rate
分类号:
R445.1；R541.61
DOI:
-
文献标识码:
A
摘要:
目的 探讨采用应变（strain, SRI）及应变率（strain rate, SR）技术评价心力衰竭患者左心室局部心肌收缩、舒张功能。方法 选取26例心力衰竭患者及30例正常对照组，采用应变及应变率技术，在心尖四腔切面，将取样点分别放置在后间隔及侧壁的基底段、中段和心尖段心肌，测量收缩期室壁不同节段的心肌应变（SRI）、收缩期应变率（SRS）、舒张早期应变率（SRE）、舒张晚期应变率（SRA）。结果 与对照组比较，心力衰竭组各节段的SRI、SRS及SRE显著降低（P<0.05, P<0.01），各节段间的SRI及SRS阶梯差消失，SRA无显著改变。结论 心力衰竭患者存在左心室收缩及舒张障碍，应变及应变率技术不失为无创定量评价的方法。
Abstract:
AIM To assess a noninvasive index to identify systolic and diastolic function of left ventricule in patients with heart failure. METHODS Certain parameters from apical fourchamber view at the basal, mid and apical of the left ventricular wall, such as peak systolic strain（SRI）, peak systolic strain rate (SRS), peak early diastolic strain rate (SRE) and peak late diastolic strain rate (SRA) were evaluated by means of strain and strain rate in 26 patients with heart failure and 30 normal subjects (control group). RESULTS Compared with those in control group, most of the parameters in heart failure group such as SRI, SRS and SRE decreased（P<0.05, P<0.01） and no significant differences were observed in SRA. The gradient of the SRI and SRS among the differential level (basal, mid and apical) of the left ventricular wall decreased or disappeared. CONCLUSION There is left ventricular systolic and diastolic dysfunction in patients with heart failure. Strain and strain rate can noninvasively and quantitatively provide information for assessment of regional myocardial function in patients with heart failure.

参考文献/References

［1］ Urheim S, Edvardsen T, Torp H, et al. Myocardial strain by Doppler echocardiography. validation of a new method to quantify regional myocardial function［J］. Circulation, 2000,102（10）:1158-1164.

［2］ Yamada E, Garcia M, Thomas JD, et al. Myocardial Doppler velocity imaging-a quantitative technique for interpretation of dobutamine echocardiography ［J］. Am J Cardiol, 1998,82（6）:806-809,A9-A10.

［3］ Yuda S, Short L, Leano R, et al. Abnormal left ventricular filling with increasing age reflects abnormal myocardial characteristics independent of ischemia or hypertrophy［J］. Am J Cardiol,2003,91（1）:63-67.

［4］ Sun JP, Popovic′ ZB, Greenberg NL, et al. Noninvasive quantification of regional myocardial function using Dopplerderived velocity, displacement, strain rate, and strain in healthy volunteers :effects of aging［J］. J Am Soc Echocardiogr, 2004,17（2）:132-138.

［5］ 吴红宁，李滨滨. 应用定量组织速度图、组织位移、应变及应变率评价正常人左心室局部心肌功能［J］.心脏杂志,2007,19（2）：222-225.

［6］ Kukulski T, Jamal F, Herbots L, et al. Identification of acutely ischemic myocardium using ultrasonic strain measurements. A clinical study in patients undergoing coronary angioplasty［J］. J Am Coll Cardiol, 2003,41（5）:810-819.

［7］ Kiraly P, Kapusta L，Thijssen JM, et al. Left ventricular myocardial function in congenital valvar aortic stenosis assessed by ultrasound tissue velocity and strain rate techniques［J］. Ultrasound Med Biol, 2003, 29(4):615-620.

［8］ GarciaFernandez MA, Azevedo J, Moreno M,et al. Regional Left Ventricular Diastolic Dysfunction Evaluated by Pulsedtissue Doppler Echocardiography［J］. Echocardiography 1999,16(5):491-500.

备注/Memo

备注/Memo:
收稿日期：2007-05-25.作者简介：吴红宁，副主任医师，硕士 Email：wuhongningdr@yahoo.com.cn
更新日期/Last Update: