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Title:: Perioperative colloid osmotic pressure changes in infants undergoing open heart surgery with cardiopulmonary bypass

作者:: 王喜明¹; 金振晓¹; 辛梅¹; 申少波²; 赵璧君¹; 毕生辉¹; 陈涛¹; 易定华¹; 1.第四军医大学西京医院心脏外科，陕西西安710032； 2.济南军区72556部队卫生队，山东济南 250022

Author(s):: WANG Ximing¹; JIN Zhenxiao¹; XIN Mei¹; SHEN Shaobo²; ZHAO Bijun¹; BI Shenghui¹; CHNE Tao¹; YI Dinghua¹; 1.Departmentment of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, Shaanxi, China; 2.Medical Team of Unit 72556, Jinan Military Area Comman, Jinan 250022, Shandong, China

关键词:: 体外循环; 胶体渗透压; 超滤; 婴幼儿

Keywords:: cardiopulmonary bypass; colloid osmotic pressure; ultrafiltration; infant

分类号:: R654.1

DOI:: -

文献标识码:: A

摘要:: 目的观察婴幼儿体外循环（CPB）心脏手术围术期胶体渗透压（COP）的变化。方法 31例婴幼儿，体质量小于10 kg，于不同时点测定血液的COP，记录动脉血氧分压、氧合指数和肺顺应性。结果 31例患儿无院内死亡，无手术相关的并发症。CPB中COP显著下降［（24±6）mmHg→（19±4）mmHg，P<005，1 mmHg=0133 kPa］，超滤结束时显著升高［（24±5） mmHg，P<001］，ICU各时间点COP维持于正常生理偏高水平，ICU 24 h显著升高［（27±6） mmHg，P<001］。结论体外循环术中婴幼儿COP下降明显，超滤可显著提高患者的COP。

Abstract:: AIM To investigate the perioperative colloid osmotic pressure changes in infants undergoing open heart surgery with cardiopulmonary bypass（CPB）. METHODS Thirtyone infant patients were enrolled in the study. Blood colloid osmotic pressure (COP) was examined at different time points and artery blood oxygen pressure (PaO2), oxygenization index (OI) and pulmonary compliances at these time points were also recorded. RESULTS No early death and other operation related complications was seen in the patients under study. COPs of patients decreased significantly during CPB ［(24±6) mmHg→(19±4) mmHg, P<005］ and increased significantly after ultrafiltration ［(24±5) mmHg, P<001］. During ICU stay, the COPs were kept at a relatively normal level but increased significantly to a higher level at the time point of 24h after ICU arrival ［(27±6) mmHg, P<001］. CONCLUSION COP decreases significantly during CPB and increases after ultrafiltration.

参考文献/References

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［7］ Ming ZD, Wei W, Hong C, et al. Banlanced ultrafitration，modified ultrafitration, and banlanced ultrafitration with modified ultrafitration in pediatric cardiopulmonary bypass ［J］. J Extra Corpor Technol, 2001, 33（4）：223-226.

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婴幼儿体外循环心脏直视手术围术期血液胶体渗透压的变化(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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