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冠心病并发Ⅱ型糖尿病患者临床及冠状动脉造影的特点(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2008年第4期
页码:
457-460
栏目:
临床研究
出版日期:
2008-08-20

文章信息/Info

Title:
Clinical characteristics and coronary angiographic findings in patients with coronary heart disease and type Ⅱ diabetes mellitus
作者:
李晶玮; 赵敏; 杜凤和; 徐秀英
首都医科大学附属北京天坛医院心内科，北京 100050
Author(s):
LI Jingwei;  ZHAO Min;  DU Fenghe;  XU Xiuying
Department of Cardiology,Beijing Tiantan Hospital,Capital Medical University,Beijing,100050,China
关键词:
冠状动脉疾病; 糖尿病; Ⅱ型; 冠状血管造影术
Keywords:
coronary disease;  type Ⅱ diabetes mellitus;  coronary angiography
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 探讨冠心病并发Ⅱ型糖尿病患者临床及冠状动脉造影特点。　方法 选择经冠状动脉造影确诊为冠心病的患者共150例，分为冠心病并发糖尿病组54例，冠心病非糖尿病组96例。对比分析两组患者的临床和冠状动脉造影资料。 结果 冠心病并发糖尿病组3支冠状动脉病变的发生率高于非糖尿病组 (54% vs 28%，P<001)；糖尿病组病变血管比例高于非糖尿病组 (59% vs 46%，P<001)；糖尿病组弥漫性病变血管的比例高于非糖尿病组 (41% vs 15%，P<001)。　结论 冠心病并发Ⅱ型糖尿病患者中并发高血压病和有心血管病家族史的比例高;多支血管病变和弥漫性病变构成比例、冠状动脉狭窄程度高于未并发Ⅱ型糖尿病患者。
Abstract:
AIM To study the clinical and coronary angiographic characteristics in patients with coronary heart diseases (CHD) and type Ⅱ diabetes mellitus. METHODS A total of 150 patients with CHD, confirmed by coronary angiography, were enrolled in this study. The patients were divided into two groups: 54 CHD patients with type Ⅱ diabetes mellitus（CHD+DM）and 96 CHD patients without type 2diabetes mellitus. The clinical features and the data from selective coronary angiographies were compared between two groups. RESULTS The changes of coronary triple vessels (54% vs 46%, P<001), the extent of coronary vessel involvement (59% vs 46%, P<001) and the diffuse vascular lesion (41% vs 15%, P<001) were significantly higher in CHD+DM group than those in CHD group. CONCLUSION The occurrence of coronary multivessel changes is more frequent in the CHD+DM group and most CHD+DM patients have narrower coronary arteries and severer diffuse lesion.

参考文献/References

［1］ Natali A, Vichi S, Landi P, et al. Coronary atherosclerosis in type Ⅱ diabetes: Angiographical findings and clinical outcome［J］. Diabetologia, 2000, 43 (5):632-641.

［2］ Johansen OE, Birkeland KI. Preventing macrovascular disease in patients with type 2 diabetes mellitus［J］. Am J Cardiovasc Drugs, 2003, 3 (4):283-297.

［3］ Hopkins PN, Wu LL, Hunt SC, et al. Higher serum bilirubin is associated with decreased risk for early familial coronary artery disease［J］. Arterioscler Thromb Vasc Biol, 1996, 16 (2):250-255.

［4］ Kaur J, Singh P, Sowers JR. Diabetes and cardiovascular disease［J］. Am J Ther, 2002, 9(6):510-515.

［5］ McGarry JD. Banting lecture 2001: Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes ［J］. Diabetes, 2002, 51(1):7-18.

［6］ Pajunen P, Nieminen MS, Taskinen MR, et al. Quantitative comparison of angiographic characteristics of coronary artery disease in patients with noninsulindependent diabetes mellitus compared with matched nondiabetic control subjects［J］. Am J Cardiol, 1997, 80(5):550-556.

［7］ Haffner SM. Coronary heart disease in patients with diabetes ［J］. N Engl J Med, 2000, 342(14):1040-1042.

［8］ 曾国彬，张玉顺，贾国良. 冠心病并发Ⅱ型糖尿病患者的冠状动脉造影特点［J］. 心脏杂志, 2002, 14(1):35-37.

［9］ Sanchez CD, Newby LK, Hasselblad V, et al. Comparison of 30 day outcome,resource use, and coronary artery disease severity in patients with suspected coronary artery disease withand without diabetes mellitus assigned to chest pain units［J］. Am J Cardiol, 2003, 91(10):1228-1230.

［10］刘海伟，韩雅玲，王效增，等. Ⅱ型糖尿病并发冠心病的临床和冠状动脉病变特点 分析［J］. 心脏杂志, 2004, 16(3):247-249.

［11］Solymoss BC, Bourassa MG, Campeau L, et al. Incidence, coronary risk profile and angiographic characteristics of prediabetic and diabetic patients in a population with ischemic heart disease［J］. Can J Cardiol, 2003, 19(10):1155-1160.

备注/Memo

备注/Memo:
收稿日期：2007-04-11.通讯作者：徐秀英，教授，主任医师，主要从事冠心病及高血压 治疗方面的研究Email：xxyddy@yahoo.com.cn 作者简介：李晶玮，主治医师，硕士Email：618ljw@sohu.com
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