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Title:: Angiographic features of coronary artery in the patients with IGT or diabetes

作者:: 刘瑛琪; 王晓非; 高铁山; 赵京涛; 刘欣波; 彭佑华; 解放军306医院心内科，北京 100101

Author(s):: LIU Yingqi; WANG Xiaofei; GAO Tieshan; ZHAO Jingtao; LIU Xinbo; PENG Youhua; Department of Cardiology, PLA 306 Hospital, Beijing 100101, China

关键词:: 口服葡萄糖耐量试验; 糖耐量异常; 空腹血糖受损; 冠状动脉造影; 冠状动脉疾病

Keywords:: oral glucose tolerance test; impaired glucose tolerance; impaired fasting glucose; coronary angiography; coronary disease

分类号:: R541.4

DOI:: -

文献标识码:: A

摘要:: 目的观察口服葡萄糖耐量试验(oral glucose tolerance test,OGTT)异常对冠心病患者冠脉病变特征的影响。方法对35例糖耐量异常(IGT)及空腹血糖受损(IFG)的冠心病患者的造影结果进行分析，并分析17例OGTT正常的冠心病患者及44例确诊糖尿病患者的冠脉造影结果。结果 3组患者的3支病变的构成比有显著差异(P<0.05,P<0.01)，远端小血管病变的发生率有显著差异(P<0.05,P<0.01)。结论 IGT(或IFG)患者在冠脉病变特征方面与OGTT正常者存在显著差异，而与糖尿病患者存在相似病变特征。

Abstract:: AIM To study the influence of abnormal glucose tolerance on angiographic characteristics of coronary artery in patients with coronary heart disease (CHD). METHODS Coronary angiographic characteristics were analyzed in 35 patients with impaired glucose tolerance (IGT) or impaired fasting glucose (IFG), 44 patients with diabetes and 17 with normal glucose tolerance. RESULTS A significant difference was observed among the IGT (or IFG) group, the normal glucose tolerance group and diabetes group in the occurrence of coronary multivessel changes and of the distal coronary changes. CONCLUSION The coronary artery lesions are of significant different severity and extent in CHD patients with abnormal and normal oral glucose tolerance test (OGTT) but are of similar characteristics of the diabetes group.

参考文献/References

[1] 阎明珠，胡大一，余金明，等. 无糖尿病病史的急性冠脉综合征患者新诊断糖代谢异常的研究［J］. 中华医学杂志， 2006， 86（18）:1256-1259.

[2] Seibaek M, Sloth C, Vallebo L, et al. Glucose tolerance status and severity of coronary artery disease in men refererd to coronary arteriography［J］. Am Heart J, 1997, 133(6):622-629.

[3] Waller BF, Palumbo PJ, Lie JT, et al. Status of the coronary artery at necropsy in diabetes mellitus with onset after 30 years: Analysis of 299 diabetic patients with and without clinical evidene of coronary heart disease and comparison 183 control subjects［J］. Am J Med, 1980, 69(4):498-506.

[4] Bartnik M, Malmberg K, Norhammar A, et al. Newly detected abnormal glucose tolerance an important predictor of longterm outcome after myocardial infarction［J］. Eur heart J, 2004, 25(22)：1990-1997.

[5] Hashimmoto K, Ikewaki K, Yagi H, et al. Glucose intolerance is common in Japanese patients with acute coronary syndrome who were not previously diagnosed with diabetes［J］. Diabetes Care, 2005, 28(5):1182-1186.

[6] 田慧，潘长玉，陆菊明，等. 糖代谢异常人群中冠心病、高血压的患病率及危险因素调查\[J\]. 中华内科杂志, 1996, 35(5):306-309.

[7] Kip KE, Faxon DP, Detre KM, et al. Coronary angioplasty in diabetic patients: The national heart,lung and blood institute percutaneous transluminal coronary angioplasty registry［J］. Circulation, 1996, 94(8):1818-1825.

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OGTT正常、异常及糖尿病患者冠状动脉造影特征比较(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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