我们的网站为什么显示成这样?

可能因为您的浏览器不支持样式,您可以更新您的浏览器到最新版本,以获取对此功能的支持,访问下面的网站,获取关于浏览器的信息:

|本期目录/Table of Contents|

ATP-敏感性钾通道的容积调控特性研究进展

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第2期
页码:
267
栏目:
综述
出版日期:
2009-03-30

文章信息/Info

Title:
-
作者:
史路平 综述王军 审校
首都医科大学基础医学院生理学教研室,北京 100069
Author(s):
-
关键词:
调节性细胞容积减小ATP-敏感性钾离子通道缺血-预适应细胞肿胀
Keywords:
-
分类号:
R543
DOI:
-
文献标识码:
A
摘要:
细胞在不同的渗透压环境下,有保持正常容积的特性。细胞容积调节是生物体细胞一个重要的生理功能。包括调节性细胞容积减小和调节性细胞容积增大。本文着重探讨在心肌细胞缺血-预适应中具有重要作用的ATP-敏感性钾通道(KATP)在细胞容积调节过程中的作用,从而探讨细胞容积调节功能与细胞缺血预适应的关系。
Abstract:
-

参考文献/References

[1] 周逸,唐其柱.ATP敏感性钾通道在缺血预适应中的作用[J]. 心脏杂志, 2005, 17(1):83-86.

[2] Minami K, Miki T, Kadowaki T, et al. Roles of ATP-sensitive K+ channels as metabolic sensors: studies of Kir6.x null mice[J]. Diabetes, 2004, 53 (3):S176-S180.

[3] Hansen AM, Hansen JB, Carr RD, et al. Kir6.2-dependent high-affinity repaglinide binding to beta-cell K(ATP)channels [J]. Br J Pharmacol, 2005, 144(4):551-557.

[4]Chan KW, Zhang H, Logothetis DE. N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits[J]. EMBO J, 2003, 22(15):3833-3843.

[5] Beheshtian A, Demehri S, Kiumehr S, et al. ATP-sensitive potassium channels mediate the anti-ischemic properties of ischemic and pharmacologic preconditioning in rat random-pattern skin flap[J]. Ann Plast Surg, 2006, 57(1):94-99.

[6] Rodrigo GC, Standen NB. ATP-sensitive potassium channels[J]. Curr Pharm Des, 2005, 11(15):1915-1940.

[7]Zhao ZQ, Zang YM. Alternative cardioprotective strategy during reperfusion: postconditioning vs preconditioning[J]. 心脏杂志, 2006, 18(1):1-7,13

[8] Petrunkina AM, Harrison RA, Ekhlasi-Hundrieser M, et al. Role of volume-stimulated osmolyte and anion channels in volume regulation by mammalian sperm[J]. Mol Hum Reprod, 2004, 10(11):815-823.

[9] Diaz RJ, Armstrong SC, Batthish M, et al. Enhanced cell volume regulation: a key protective mechanism of ischemic preconditioning in rabbit ventricular myocytes[J]. J Mol Cell Cardiol, 2003, 35(1):45-58.

[10]Wajima T, Shimizu S, Hiroi T, et al. Reduction of myocardial infarct size by tetrahydrobiopterin: possible involvement of mitochondrial KATP channels activation through nitric oxide production[J]. Mol Hum Reprod, 2004, 10(11):815-823.

[11]Kocic I. Modulators of ion channels activated by hypotonic swelling in cardiomyocytes: new perspectives for pharmacological treatment of life-threatening arrhythmias[J]. Curr Med Chem Cardiovasc Hematol Agents, 2005, 3(4):333-339.

[12]Kocic I, Hirano Y, Hiraoka M. Hypotonic stress increases efficacy of rilmakalim, but not pinacidil, to activate ATP-sensitive K+ current in guinea pig ventricular myocytes[J]. J Pharmacol Sci, 2004, 95(2):189-195.

[13]高渊,郑强荪,雷靖袆,等. KATP通道阻断剂对兔缺血心室肌跨壁离散度的影响[J]. 心脏杂志, 2007, 19(2):139-142.

[14]Mizutani S, Prasad SM, Sellitto AD, et al. Myocyte volume and function in response to osmotic stress observations in the presence of an adenosine triphosphate-sensitive potassium channel opener[J]. Circulation, 2005, 112(9):219-223.

[15]Liu J, Long C, Ji B, et al. Myocardial protective effects of nicorandil, an opener of potassium channels on senile rat heart[J]. Perfusion, 2006, 21(3):179-183.

[16]Okada SF, Nicholas RA, Kreda SM, et al. Physiological regulation of ATP release at the apical surface of human airway epithelia[J]. J Biol Chem, 2006, 281(32):22992-23002.

备注/Memo

备注/Memo:
收稿日期:2007-7-2.基金项目:国家自然科学基金(30670765)和北京市自然科学基金(07G0035)项目资助 通讯作者:王军,教授,主要从事循环电生理研究Email:wangjun@ccmu.edu.cn 作者简介:史路平,硕士生Email:shiluping163@163.com
更新日期/Last Update: 2009-04-16